DRSC/TRiP Functional Genomics Resources

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Protein Alignment Art1 and Prmt9

DIOPT Version :10

Sequence 1:NP_650017.1 Gene:Art1 / 41295 FlyBaseID:FBgn0037834 Length:376 Species:Drosophila melanogaster
Sequence 2:NP_001074709.1 Gene:Prmt9 / 102182 MGIID:2142651 Length:846 Species:Mus musculus


Alignment Length:371 Identity:90/371 - (24%)
Similarity:150/371 - (40%) Gaps:72/371 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly    13 ESATGITPNSNANSNNVAKKLPAEGSTGD-----------NPNANADEMTSRDYYFDSYAHFGIH 66
            |.|..:.|:.....|::.:.|...|...:           ||:.|  :.....|...::.....|
Mouse    91 EQALELFPDDEVICNSMGEHLFRMGFRDEAAGYFHKAVKLNPDFN--DAKENFYRVANWLVERWH 153

  Fly    67 EEMLKDEVRTVTYRNAMYHNKHLFQGKTVLDVGCGTGILSMFAAKAGAAQVIAVDCS-NIIEFAR 130
            ..||.|..|.:.| ||..........:||||:|.|||||||||.||||..|.|.:.| .:.|.|.
Mouse   154 FIMLNDTRRNMVY-NAAIQKAVCLGSRTVLDIGTGTGILSMFAKKAGAQSVYACELSKTMYELAC 217

  Fly   131 QVVIDNNLQDVITVVKGKIEEIELPNGI-EGVDIIISEWMGYCLFYESMLDTVLYARDKWL---- 190
            .||..|.:::.|.::..|..:||:|..| |.|.::::|.:...:|.|.:::::::|.:..|    
Mouse   218 DVVAANKMENGIKLLHMKSLDIEIPKHIPERVSLVVTETVDAGVFGEGIVESLIHAWEHLLLQPK 282

  Fly   191 --------KKDGMMFPDRGTLYITAIEDRQYKDEKINWWDDVYGFDMSCIRKVAVTEPLVDVVDP 247
                    .|.|.:.|....::..|:|..:.:........|:.|..:.  ..|....|....||.
Mouse   283 TKEENGNCGKYGKVIPAGAVIFGMAVECAEIRRHHRVGAKDIAGIHLP--TNVKFQSPAYTSVDT 345

  Fly   248 KQVVS-----------------TSCMVKEVDLYTVQKADLNFSSKF-SLCIK----------RND 284
            ::.|.                 |.|       :.:.|.|.|...:. ||..|          :..
Mouse   346 EETVEPYTTEKMSGIPGGYLPLTEC-------FQIMKVDFNNLQELKSLATKKPHSLNVPAIKEG 403

  Fly   285 FVQALVTYFNIEFTKCHKRLGFSTSPDSTYTHWKQTVF---YLDDH 327
            .:.|::.:|.::.   ......|||| |..|.|:|.|:   .|:|:
Mouse   404 VLDAIMVWFVLQL---DDEYSLSTSP-SEETCWEQAVYPVQALEDY 445

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Art1NP_650017.1 COG4076 66..>231 CDD:443253 54/178 (30%)
Prmt9NP_001074709.1 TPR 1 25..58
TPR <40..>140 CDD:440225 9/50 (18%)
TPR 2 67..100 3/8 (38%)
TPR repeat 68..95 CDD:276809 2/3 (67%)
TPR repeat 100..130 CDD:276809 3/29 (10%)
TPR 3 101..134 5/32 (16%)
COG4076 148..>319 CDD:443253 52/171 (30%)
Blue background indicates that the domain is not in the aligned region.

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