DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rbp1 and RBM4B

DIOPT Version :9

Sequence 1:	NP_731510.1	Gene:	Rbp1 / 41294	FlyBaseID:	FBgn0260944	Length:	144	Species:	Drosophila melanogaster
Sequence 2:	NP_113680.1	Gene:	RBM4B / 83759	HGNCID:	28842	Length:	359	Species:	Homo sapiens

Alignment Length:	181	Identity:	43/181 - (23%)
Similarity:	65/181 - (35%)	Gaps:	62/181 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 KVYVGNLGSSASKHEIEGAFAKYGPLRNVWVARNPPGFAFVEFEDRRDAEDATRALDGTRCCGTR 76
            |::|||:..:.:..|:...|.:|||:....:.::   :|||..|...||.:|.|.||.|...|.|
Human    79 KLHVGNISPTCTNQELRAKFEEYGPVIECDIVKD---YAFVHMERAEDAVEAIRGLDNTEFQGKR 140

  Fly    77 IRVEMSSGRSRDRRRGEGGSSG-----------------RSGS---------------------- 102
            :.|::|:.|.| ...|.|..||                 |:|.
Human   141 MHVQLSTSRLR-TAPGMGDQSGCYRCGKEGHWSKECPVDRTGRVADFTEQYNEQYGAVRTPYTMG 204

  Fly   103 -----------------GRYRITPSARTTSTATSSFYNINNLQQQPSSQPQ 136
                             .|||:.......:.|.:|.||.  .:|..|..||
Human   205 YGESMYYNDAYGALDYYKRYRVRSYEAVAAAAAASAYNY--AEQTMSHLPQ 253

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rbp1	NP_731510.1	RRM_SRSF3_like	12..81	CDD:409808	23/68 (34%)
RBM4B	NP_113680.1	RRM1_RBM4	2..68	CDD:410018
		RRM2_RBM4	78..144	CDD:410019	22/67 (33%)
		PTZ00368	<145..>181	CDD:173561	8/36 (22%)
		ZnF_C2HC	161..176	CDD:197667	1/14 (7%)
		Interaction with TNPO3. /evidence=ECO:0000250	196..359		11/60 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910