Protein Alignment Rbp1 and RBM4

DIOPT Version :10

• Sequence 1: NP_731510.1
• Gene: Rbp1 / 41294
• FlyBaseID: FBgn0260944
• Length: 144
• Species: Drosophila melanogaster
• Sequence 2: NP_002887.2
• Gene: RBM4 / 5936
• HGNCID: 9901
• Length: 364
• Species: Homo sapiens
• Alignment Length: 138
• Identity: 41/138 - (29%)
• Similarity: 60/138 - (43%)
• Gaps: 30/138 - (21%)

  Fly    12 KVYVGNLGSSASKHEIEGAFAKYGPLRNVWVARNPPGFAFVEFEDRRDAEDATRALDGTRCCGTR 76
            |::|||:..:.:..|:...|.:|||:....:.::   :|||..|...||.:|.|.||.|...|.|
Human    79 KLHVGNISPTCTNKELRAKFEEYGPVIECDIVKD---YAFVHMERAEDAVEAIRGLDNTEFQGKR 140

  Fly    77 IRVEMSSGRSRDRRRGEGGSSG--RSG-------------SGR-----------YRITPSARTTS 115
            :.|::|:.|.| ...|.|..||  |.|             |||           |....:..|.|
Human   141 MHVQLSTSRLR-TAPGMGDQSGCYRCGKEGHWSKECPIDRSGRVADLTEQYNEQYGAVRTPYTMS 204

  Fly   116 TATSSFYN 123
            ...|.:||
Human   205 YGDSLYYN 212

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rbp1	NP_731510.1	RRM_SRSF3_like	12..81	CDD:409808	23/68 (34%)
RBM4	NP_002887.2	RRM1_RBM4	2..68	CDD:410018
		RRM2_RBM4	78..144	CDD:410019	22/67 (33%)
		PTZ00368	<145..>181	CDD:173561	9/36 (25%)
		ZnF_C2HC	161..176	CDD:197667	3/14 (21%)
		Interaction with TNPO3. /evidence=ECO:0000269|PubMed:12628928	196..364		5/17 (29%)