Protein Alignment Cap-H2 and ncaph2

DIOPT Version :9

• Sequence 1: NP_650014.2
• Gene: Cap-H2 / 41289
• FlyBaseID: FBgn0037831
• Length: 960
• Species: Drosophila melanogaster
• Sequence 2: NP_001038456.1
• Gene: ncaph2 / 562678
• ZFINID: ZDB-GENE-041210-172
• Length: 592
• Species: Danio rerio
• Alignment Length: 876
• Identity: 161/876 - (18%)
• Similarity: 279/876 - (31%)
• Gaps: 337/876 - (38%)

  Fly    47 ASLVVLLEELSKNTDYSTDLRISLGYYIEELLRHCL----GRNDVS-RRSAIVAAGSALQYCGKI 106
            |.|:..|.:|:||.|  .||...||.|:|||.:..:    |:..:: ..:|::..||.   |  |
Zfish     9 AHLLQPLRDLTKNWD--IDLASQLGEYLEELDQMTISFDGGKTMMNFAEAALLIQGST---C--I 66

  Fly   107 YGDRVEYLCQVVEHQIEALLTSELQKETPSGSAAPEKNERRPEETRKRHPKKLTNKEVDPYLLTL 171
            ||.:||.|..:|...:: .::::.:|....||::....|:.|           :..|.|..
Zfish    67 YGRKVELLHTLVFQTLD-YISNKNKKRDKQGSSSDGNQEQAP-----------SGSEGDGC---- 115

  Fly   172 EPKRFKTMSDDKRFNAAGFVKCTRNRTIEYLYQDHTPPNLWKHAPIVDPHN--PYDQDEKKQYKM 234
               .|..:..|:..|       |.|.|:    :|.|.|......|   |.:  |.:..||::|.:
Zfish   116 ---EFDEIEQDENVN-------THNITM----KDPTEPVRIIRLP---PESLIPAESHEKQKYPL 163

  Fly   235 FTYHVEHRYNTLLPDIPFERLNLIKEYVHTNQVNTTEILNEHMTTKEYLDEYIALENQMLAARYG 299
            .:             :..|.|...|::    ::||..           :||
Zfish   164 LS-------------LKGELLGSCKDF----RINTFT-----------MDE-------------- 186

  Fly   300 AIVTRRRRLVDSARFMEDNLDEGLAKKMCMDKNLPMDTNETVLIDQSLVDENSRSLTTAESTMGI 364
               ....||..:..|:     :|:|:   :.::..:...|.:.|
Zfish   187 ---AGLMRLGSNTHFL-----KGVAE---VQRDFSVHLPEPLQI--------------------- 219

  Fly   365 SQAENSTLKSSEVEATLSVSHIENSLSDSQEENPPLSSTLAINESSVLDSTRVDPIKDLTLDELL 429
                       |.||..:....:..:....|..|||.
Zfish   220 -----------EGEAAAANGGYDEEVDGGAEVLPPLE---------------------------- 245

  Fly   430 LIDSGISMEELSDIQMHTAGQSFDDEGVVLSDLEDQRQLSPMLQMVS--PSMEAKTLNIIEMDAD 492
              |.|:.:|....::.|.|    ..||.:|       :..|.:|.||  |....:|::
Zfish   246 --DHGMEVESDEWVERHEA----PSEGRML-------RPRPAVQPVSEEPKQLKETVD------- 290

  Fly   493 LIMNVPREVSYPILLNVMGLPIKRLRRKCIFKLPPEFDLFRQARLPIKREGQQKSPTTPRTVLQI 557
                 |.::..|........|:|  ..|| :|:|...|          ..|::|
Zfish   291 -----PWKLHDPYATFGEDKPLK--AGKC-YKVPAGLD----------ESGKRK----------- 326

  Fly   558 GREAPQNEREPGSPCSLEFD------------EDLNFL-------------GFRQRRPTFDSGFD 597
             |:.|...::.|:..:..|:            .|||::             ...::|..|.|..:
Zfish   327 -RKGPSKLQDFGTWFNKAFETADRKLKNGPTFPDLNYIFVSKMDQRLKVQRQMLRKRGVFVSDEE 390

  Fly   598 IE----EPRVSSCVSTIGEVKTELEDEIEANTNNLTDASASDALNENVNDTKESGLGDSLAQELN 658
            ::    ||.             .:||::|...:       .||..::.:|.:...|.|.|
Zfish   391 LKKTYLEPE-------------NVEDQVEVIRH-------PDADGDDYSDEEHDNLADDL----- 430

  Fly   659 ASTEPNAENNTANSSQLEVTATESSGTLSGLETTVDLGMESALVSSVLDLSTEPSAMDSNIINVT 723
               || ||:                                      ||        |...|
Zfish   431 ---EP-AEH--------------------------------------LD--------DQEQI--- 442

  Fly   724 QPDNSDLEISTVQDQDTLHDEADANDLSAETPNPIADSAVDDCSL---IRDWHRRLAPALEAAHE 785
               ..||.:|.:..:|.:....|...::::       ....:.:|   ::||...:.|.|.|...
Zfish   443 ---FQDLHMSRMSYEDLVKKSVDLFLVNSQ-------KYAQETALSRRVKDWEDSINPHLAAQEI 497

  Fly   786 RQNFNIKDLGTEILDICKAGNRTATLADVMADKDPSIMCRYMLASLVLTNHGNVSLDFENRDKSK 850
            ...|:|.:.|..|:..........:.|.|:..|:.:..||||||:|.|.|...|.:     ||..
Zfish   498 SPAFDIHEYGDRIVHALSNVGVKKSFAFVVRGKENTEACRYMLAALQLANDYTVEV-----DKVD 557

  Fly   851 PIDMSQFRMHLKSMKRMEINPEDDVGNINAA 881
            .:|.|...|.|..:.....:......|..||
Zfish   558 GLDCSVDTMELTLLTTQRAHERLKTYNATAA 588

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cap-H2	NP_650014.2	CNDH2_C	<769..844	CDD:293463	22/74 (30%)
ncaph2	NP_001038456.1	CNDH2_N	11..124	CDD:283849	34/138 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	89..116		7/44 (16%)
		CNDH2_M	145..>188	CDD:293474	13/90 (14%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	261..285		9/34 (26%)
		CNDH2_C	291..573	CDD:293463	74/399 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2359
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005551
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR14324
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2597
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	4.030