Protein Alignment Cap-H2 and Ncaph2

DIOPT Version :9

• Sequence 1: NP_650014.2
• Gene: Cap-H2 / 41289
• FlyBaseID: FBgn0037831
• Length: 960
• Species: Drosophila melanogaster
• Sequence 2: XP_017450267.1
• Gene: Ncaph2 / 300149
• RGDID: 1565937
• Length: 627
• Species: Rattus norvegicus
• Alignment Length: 670
• Identity: 123/670 - (18%)
• Similarity: 229/670 - (34%)
• Gaps: 194/670 - (28%)

  Fly   274 NEHMTTKEYLDEYIALENQ----------MLAARYGAI--VTRRRRLVDSARFMEDNLDEGLAKK 326
            :|..||..:::..:.::..          :.:..|.|:  ::.:||....:...||      ...
  Rat    67 DEGKTTMNFIEAALLIQGSACVYSKKVEYLYSLVYQALDFISGKRRAKQLSLVQED------GSN 125

  Fly   327 MCMDKNLPMDTNETVLIDQSLVD-ENSRSLTTAESTMGISQAENSTLKSSEVEATLSV------- 383
            ..::...|.:|.:..|   ||.| .:||:              |..||:.:..:.|.:
  Rat   126 RAVNSGTPCETEDEFL---SLDDFPDSRA--------------NVDLKNDQASSELLIIPLLPMA 173

  Fly   384 ----SHIENSLSDSQEENPPLS---STLAINESSVLDSTRVDPIKDLTLDELLLIDSGISMEELS 441
                ..:|.|      .||..|   ..||..:...:::...||.....||.       :.|..:.
  Rat   174 LVAPDEVEKS------SNPLYSCQGEVLASRKDFRMNTCTPDPRGSFMLDP-------VGMCPVE 225

  Fly   442 DIQMHTAGQSFDDEGVVLSDLEDQ-----RQLSPM-LQMVSPSMEAKTLNIIEMDADLIMNVPRE 500
            .:.:|...:|..|    ..:.|:|     |..||: ::.:|...:...|:..:.||:.:..:| |
  Rat   226 PVDVHPMPRSQKD----AEEAEEQPMAVSRNGSPVSVRSISQEPDGPALSSGDEDAEDVAELP-E 285

  Fly   501 VSYPILLNVMGLPIKRLRRKCIFKLPPEFDLFRQARLPIKREGQQKSP----------TTPRTVL 555
            |:..        |.:....:....||..:.|..:...|......|::|          :....:.
  Rat   286 VALE--------PAEPRTSQQTAILPRRYMLRERQGAPEPASQPQETPDPWQSLDPFDSLDSKLF 342

  Fly   556 QIGR---------EAPQNEREPGSPCSLE---------FDEDLNFLGFRQRRPTFDSGFDIEEPR 602
            |.|:         |||..:|:......|:         :.|..:....|::.|:|   .|:|
  Rat   343 QKGKPYSVPPGVEEAPGQKRKRKGATKLQDFHQWYLDAYAEHPDGRRARRKGPSF---ADME--- 401

  Fly   603 VSSCVSTIGEVKTELEDEIEANTNNLTDASASDALNENVNDTKESGLGDSLAQELNASTEPNAEN 667
                |.....||.:||...:.....:|:.....| .:::...:|..|.:.| ::|..:.:...|
  Rat   402 ----VLYWKHVKEQLETLQKLRRRKMTERWLPGA-KQDLWPAEEERLEEPL-EDLGVAADDFLE- 459

  Fly   668 NTANSSQLEVTATESSGTLSGLETTVDLGMESALVSSVLDLSTEPSAMDSNIINVTQPD------ 726
                   .|....||.|.                      :..|.:.:|:..|    |:
  Rat   460 -------AEEYVEESEGV----------------------MPREAAGLDAEAI----PESLKYEE 491

  Fly   727 ----NSDLEISTVQD--QDTLHDEADANDLSAETPNPIADSAVDDCSLIRDWHRRLAPALEAAHE 785
                |.:|.|:|.|.  |:|        :||..               ||||...:.|.|:...:
  Rat   492 LVRRNVELFIATSQKFIQET--------ELSQR---------------IRDWEDTIQPLLQEQEQ 533

  Fly   786 RQNFNIKDLGTEILDICKAGNRTATLADVMADKDPSIMCRYMLASLVLTNHGNVSLDFENRDKSK 850
            ...|:|...|.:::......|.....|:::|.:....:||.|||||.|.|...|.:. :......
  Rat   534 HVPFDIHTYGDQLVSRFPQLNEWCPFAELVAGQPAFEVCRSMLASLQLANDYTVEIT-QQPGLEA 597

  Fly   851 PIDMSQFRM--HLKSMKRME 868
            .:|....|:  |.::..|.:
  Rat   598 AVDTMSLRLLTHQRAHMRFQ 617

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cap-H2	NP_650014.2	CNDH2_C	<769..844	CDD:293463	22/74 (30%)
Ncaph2	XP_017450267.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2359
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005551
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR14324
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.000