Protein Alignment CG14691 and QDR1

DIOPT Version :10

• Sequence 1: NP_650012.2
• Gene: CG14691 / 41287
• FlyBaseID: FBgn0037829
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_012146.1
• Gene: QDR1 / 854686
• SGDID: S000001382
• Length: 563
• Species: Saccharomyces cerevisiae
• Alignment Length: 579
• Identity: 123/579 - (21%)
• Similarity: 209/579 - (36%)
• Gaps: 167/579 - (28%)

  Fly     2 ADRAKDNTDEPADFETAI-AECGFGL--FNVFI----LCSAVPCLTAMVFSASALSYVMPSAECD 59
            :|...||..|.::..:.| .|..|.:  ::.|.    :...|.|.....||..|.|...|.
Yeast    32 SDAISDNDAERSNSHSEIDNESNFDMVPYSRFSHKQKMLLVVQCAFTGFFSTVAGSIYYPV---- 92

  Fly    60 LDLSIVDKGM-----LHAVT------YAGMIISAVPWGFIADTIGRRPVLISGGW-LDGFFVLCA 112
              |:|:::..     |..||      :.|:..|.:  |.:|||.||||:::   | :..:|..|.
Yeast    93 --LTIIERKFNITEELANVTIVVYFIFQGVAPSIM--GGLADTFGRRPIVL---WAILAYFCACI 150

  Fly   113 SL--SQNTAQLMAFKFFDGLIICGPFAVVVSYLAEFHGKKHR-PYIMLFVGLCV---SIGSMILP 171
            .|  :.|.||::|.:......|....|:....:.:...|..| .|:.|..|..|   :.|::|..
Yeast   151 GLACAHNYAQILALRCLQAAGISPVIAINSGIMGDVTTKVERGGYVGLVAGFQVVGTAFGALIGA 215

  Fly   172 LLSYLLLPVPILFTVSSMKFRTWQVFLAVSSAPSLLSGFLHIFLPESPKFLMSQGNYKKALDSLQ 236
            .||            |...:|....|||:.|...|:  |..:.:||:.:.|:..|:.... ..|.
Yeast   216 GLS------------SKWGWRAIFWFLAIGSGICLV--FSTLLMPETKRTLVGNGSVTPR-SFLN 265

  Fly   237 RIYKLNKRKSRESYPIKHLTDPTPDRSDDLDGTGRPSTLQERFSRAQSKFIDGFKQLKPM----- 296
            |...|:....:::.   ||.||.|:            ||:.|.|      :|....||.:
Yeast   266 RSLILHVGSVKKTL---HLDDPDPE------------TLEPRTS------VDFLAPLKILHIREI 309

  Fly   297 ----------FSS-----PYLAISL-QVYCLHFCQI-MCVNSVRLWLPQIFATMNAMDTLG--AN 342
                      ||:     ..|.|.| :.|.|...:| :|      :||...:|:.::.:.|  .|
Yeast   310 DILLSIAGLQFSTWTTHQTALTIVLSKKYNLSVAKIGLC------FLPAGISTLTSIISAGRYLN 368

  Fly   343 DTSMCAVLEHNANAKSMD-------EEEKRVECALHHDPDSYLNNITVAGIGLVGFLIIFPLMRF 400
            .:.....:::|...|..:       :.:|.....|.|....|                     .|
Yeast   369 WSYRTRKVKYNRWIKEQELQLMEKYKGDKNKVAELIHSNSHY---------------------AF 412

  Fly   401 QVVSNHILKVFLFICIFLVGSLYF-----VKTSLVTMMVSAVYLTMMGIC----ATTIIGMSVVI 456
            .:|...:...|:.:.:..:|...|     |||.|..::.::.:.::...|    :||:|   |.:
Yeast   413 NLVEARLHPAFVTLLLSSIGFTAFGWCISVKTPLAAVLCTSAFASLFSNCILTFSTTLI---VDL 474

  Fly   457 FPTLMRTMVLLLIMTFGRLGSVSGNMLLPVFMQLSCLAPFLWLCSLMSIAFLFSLFLKV 515
            ||:...|..                         .||..|..|.|.:.||.|..:..|:
Yeast   475 FPSKASTAT-------------------------GCLNLFRCLLSAIFIAALTKMVEKM 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14691	NP_650012.2	synapt_SV2	2..>337	CDD:130366	89/381 (23%)
		MFS	<375..513	CDD:475125	26/146 (18%)
QDR1	NP_012146.1	MFS_Tpo1_MDR_like	72..516	CDD:340881	115/539 (21%)