Protein Alignment CG14691 and SLC22A5

DIOPT Version :9

• Sequence 1: NP_650012.2
• Gene: CG14691 / 41287
• FlyBaseID: FBgn0037829
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_001295051.1
• Gene: SLC22A5 / 6584
• HGNCID: 10969
• Length: 581
• Species: Homo sapiens
• Alignment Length: 469
• Identity: 104/469 - (22%)
• Similarity: 187/469 - (39%)
• Gaps: 139/469 - (29%)

  Fly    75 YAGMIISAVPWGFIADTIGRRPVL-ISGGWLDGFFVLCASLSQNTAQLMAFKFFDGLIICGPFAV 138
            :.|:::.:...|.::|..||:.|| ::.|...||..| ...|:|      |:.|..|.:......
Human   174 FVGVLLGSFISGQLSDRFGRKNVLFVTMGMQTGFSFL-QIFSKN------FEMFVVLFVLVGMGQ 231

  Fly   139 VVSYLA------EFHGKKHRPYIMLFVGLCV--SIGSMILPLLSYLLLPVPILFTVSSMKFRTWQ 195
            :.:|:|      |..||..| .|...:|:|:  :.|.|:|||.:|.:              |.|:
Human   232 ISNYVAAFVLGTEILGKSVR-IIFSTLGVCIFYAFGYMVLPLFAYFI--------------RDWR 281

  Fly   196 VFLAVSSAPSLLSGFLHIFLPESPKFLMSQGNYKKALDSLQRIYKLNKRKSRESYPIKHLTDPTP 260
            :.|...:.|.:|...|..|:||||::|:|||.:::|...:::..|.|
Human   282 MLLVALTMPGVLCVALWWFIPESPRWLISQGRFEEAEVIIRKAAKAN------------------ 328

  Fly   261 DRSDDLDGTGRPSTLQERFSRAQSKFIDGFKQLKPMFSSPYLAISLQVYCLHFCQIMCVNSVRLW 325
                   |...|||:   |..::.:.:...||     .|..:...|:.:.:....||   |:.||
Human   329 -------GIVVPSTI---FDPSELQDLSSKKQ-----QSHNILDLLRTWNIRMVTIM---SIMLW 375

  Fly   326 LPQIFATMNAMDTLGANDTSMCAVLEHNANAKSMDEEEKRVECALHHDPDSYLNNITVAGIGLVG 390
            :           |:......:           |:|...      ||  .|.::|....|.:.:..
Human   376 M-----------TISVGYFGL-----------SLDTPN------LH--GDIFVNCFLSAMVEVPA 410

  Fly   391 FLIIFPLMRFQVVSNHILKVFLFICIFLVGS-----------LYFVKTSL-------VTMMVSAV 437
            :::.:.|:::..     .:..:...:||.||           ||::.|.|       ||...|.|
Human   411 YVLAWLLLQYLP-----RRYSMATALFLGGSVLLFMQLVPPDLYYLATVLVMVGKFGVTAAFSMV 470

  Fly   438 YLTMMGICATTIIGMSVVIFPTLMRTMVLLLIMTFGRLGSVSGNMLLPVFMQLSC---LAPFLWL 499
            |:            .:..::||::|.|.:.:..|..||||:    |.|.|:.|..   ..|::.:
Human   471 YV------------YTAELYPTVVRNMGVGVSSTASRLGSI----LSPYFVYLGAYDRFLPYILM 519

  Fly   500 CSLMSIAFLFSLFL 513
            .||..:..:.:|||
Human   520 GSLTILTAILTLFL 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14691	NP_650012.2	MFS	30..>216	CDD:119392	38/149 (26%)
SLC22A5	NP_001295051.1	2A0119	12..544	CDD:273328	104/469 (22%)
		MFS	162..534	CDD:119392	104/469 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153575
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.850