Protein Alignment CG14691 and SLC22A4

DIOPT Version :9

• Sequence 1: NP_650012.2
• Gene: CG14691 / 41287
• FlyBaseID: FBgn0037829
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_003050.2
• Gene: SLC22A4 / 6583
• HGNCID: 10968
• Length: 551
• Species: Homo sapiens
• Alignment Length: 497
• Identity: 107/497 - (21%)
• Similarity: 198/497 - (39%)
• Gaps: 125/497 - (25%)

  Fly    38 CLTAMVFSASA-LSYVMPSAECDLDLSIVDKGMLHAVT---YAGMIISAVPWGFIADTIGRRPVL 98
            ||....||... ||.|:    .:.:|...|...:...|   :.|:::.:...|.::|..||:.||
Human   113 CLDGWEFSQDVYLSTVV----TEWNLVCEDNWKVPLTTSLFFVGVLLGSFVSGQLSDRFGRKNVL 173

  Fly    99 ISGGWLDGFFVLCASLSQNTAQL--MAFKFFDGLIICGPFAVVVSYL------AEFHGKKHRPYI 155
                    |..:......:..|:  ::::.|..|.:......:.:|:      .|..||..| .|
Human   174 --------FATMAVQTGFSFLQIFSISWEMFTVLFVIVGMGQISNYVVAFILGTEILGKSVR-II 229

  Fly   156 MLFVGLCV--SIGSMILPLLSYLLLPVPILFTVSSMKFRTWQVFLAVSSAPSLLSGFLHIFLPES 218
            ...:|:|.  ::|.|:|||.:|.:              |.|::.|...:.|.:|...|..|:|||
Human   230 FSTLGVCTFFAVGYMLLPLFAYFI--------------RDWRMLLLALTVPGVLCVPLWWFIPES 280

  Fly   219 PKFLMSQGNYKKALDSLQRIYKLNKRKSRESYPIKHLTDPTPDRSDDLDGTGRPSTLQERFSRAQ 283
            |::|:||..:::|.|.:|:..|:|           ::..|
Human   281 PRWLISQRRFREAEDIIQKAAKMN-----------NIAVP------------------------- 309

  Fly   284 SKFIDGFKQLKPMFSSPYLAISLQVYCLHFCQIMCVNSVRLWLPQIFATMNAMDTLGANDTSMCA 348
            :...|..::|.|:  ....|..|.::......||.:.|:.||:         :.::|....|:.|
Human   310 AVIFDSVEELNPL--KQQKAFILDLFRTRNIAIMTIMSLLLWM---------LTSVGYFALSLDA 363

  Fly   349 VLEHNANAKSMDEEEKRVECALHHDPDSYLNNITVAGIGLVGFLIIFPLMRFQVVSNHILKVFLF 413
            ...|.                     |:|||....|.|.:..::..:.|:| .:...:|:...||
Human   364 PNLHG---------------------DAYLNCFLSALIEIPAYITAWLLLR-TLPRRYIIAAVLF 406

  Fly   414 ICIFLVGSLYFVKTSLVTMMVSAVYLTMMG-ICATTIIGMSVV----IFPTLMRTMVLLLIMTFG 473
               :..|.|.|::...|.....::.|.|:| ...|:...|..|    ::|||:|.|.:.:..|..
Human   407 ---WGGGVLLFIQLVPVDYYFLSIGLVMLGKFGITSAFSMLYVFTAELYPTLVRNMAVGVTSTAS 468

  Fly   474 RLGSVSGNMLLPVFMQLSC---LAPFLWLCSLMSIAFLFSLF 512
            |:||:    :.|.|:.|..   :.|::.:.||..:..:.:||
Human   469 RVGSI----IAPYFVYLGAYNRMLPYIVMGSLTVLIGILTLF 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14691	NP_650012.2	MFS	30..>216	CDD:119392	42/191 (22%)
SLC22A4	NP_003050.2	2A0119	12..518	CDD:273328	107/497 (22%)
		MFS	123..508	CDD:119392	103/487 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153574
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.850