Protein Alignment CG14691 and SLC22A2

DIOPT Version :9

• Sequence 1: NP_650012.2
• Gene: CG14691 / 41287
• FlyBaseID: FBgn0037829
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_003049.2
• Gene: SLC22A2 / 6582
• HGNCID: 10966
• Length: 555
• Species: Homo sapiens
• Alignment Length: 484
• Identity: 103/484 - (21%)
• Similarity: 182/484 - (37%)
• Gaps: 128/484 - (26%)

  Fly    37 PCLTAMVFSASALSYVMPSAECDLDLSIVDKGML---HAVTYAGMIISAVPWGFIADTIGRRPVL 98
            ||....|:.....|.|     .:.:|...:..||   .:....|..|.::..|:|||..||:..|
Human   121 PCRDGWVYETPGSSIV-----TEFNLVCANSWMLDLFQSSVNVGFFIGSMSIGYIADRFGRKLCL 180

  Fly    99 ISGGWLDGFFVLCASLSQNTAQLMAFKFFDGLIICGPFAVVVSYLAEFHGKKHRPYIMLFVGLCV 163
            ::...::....:..::|.....::.|:...||:....:.:....:.||.|:::|..:.:|..:..
Human   181 LTTVLINAAAGVLMAISPTYTWMLIFRLIQGLVSKAGWLIGYILITEFVGRRYRRTVGIFYQVAY 245

  Fly   164 SIGSMILPLLSYLLLPVP----ILFTVSSMKFRTWQVFLAVSSAPSLLSGFLHIFLPESPKFLMS 224
            ::|.::|..::|.|   |    :.||||...|    .||           ..:..:||||::|:|
Human   246 TVGLLVLAGVAYAL---PHWRWLQFTVSLPNF----FFL-----------LYYWCIPESPRWLIS 292

  Fly   225 QGNYKKALDSLQRIYKLNKRKSRESYPIKHLTDPTPDRSDDLDGTGRPSTLQERFSRAQSKFIDG 289
            |....:|:..::.|.|.|                         |...|::||    |.:.:...|
Human   293 QNKNAEAMRIIKHIAKKN-------------------------GKSLPASLQ----RLRLEEETG 328

  Fly   290 FKQLKPMFSSPYLAISLQVYCLHFCQIMCVNSVRLWLPQIFA-TMNAMDTLGANDTSMCAVLEHN 353
             |:|.|.|                     ::.||  .|||.. ||               :|.:|
Human   329 -KKLNPSF---------------------LDLVR--TPQIRKHTM---------------ILMYN 354

  Fly   354 ANAKSMDEEEKRVECALHHDPDSYLNNITVAGIGL-VGFLIIFPLMRF-----QVVSNHILKVFL 412
            ....|:..:...:...|..| :.||:....|.:.. ..|:||..:.|.     ...||.:.....
Human   355 WFTSSVLYQGLIMHMGLAGD-NIYLDFFYSALVEFPAAFMIILTIDRIGRRYPWAASNMVAGAAC 418

  Fly   413 FICIFLVGSLYFVKTSL-------VTMMVSAVYLTMMGICATTIIGMSV-----------VIFPT 459
            ...:|:.|.|.::|..:       :||....|.|....:..|.|..:.|           :|.|.
Human   419 LASVFIPGDLQWLKIIISCLGRMGITMAYEIVCLVNAELYPTFIRNLGVHICSSMCDIGGIITPF 483

  Fly   460 LMRTM----VLLLIMTFGRLGSVSGNMLL 484
            |:..:    :.|.:|.||.||.|:|.::|
Human   484 LVYRLTNIWLELPLMVFGVLGLVAGGLVL 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14691	NP_650012.2	MFS	30..>216	CDD:119392	38/185 (21%)
SLC22A2	NP_003049.2	2A0119	13..525	CDD:273328	103/484 (21%)
		MFS	124..492	CDD:119392	92/459 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153564
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.850