Protein Alignment CG14691 and SLC22A1

DIOPT Version :9

• Sequence 1: NP_650012.2
• Gene: CG14691 / 41287
• FlyBaseID: FBgn0037829
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: XP_005267159.1
• Gene: SLC22A1 / 6580
• HGNCID: 10963
• Length: 610
• Species: Homo sapiens
• Alignment Length: 471
• Identity: 87/471 - (18%)
• Similarity: 170/471 - (36%)
• Gaps: 117/471 - (24%)

  Fly    37 PCLTAMVFSASALSYVMPSAECDLDLSIVDK---GMLHAVTYAGMIISAVPWGFIADTIGRRPVL 98
            ||....|:.....|.|     .:.:|...|.   .:..:...||.:..::..|:.||..||:..|
Human   120 PCQDGWVYDTPGSSIV-----TEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCL 179

  Fly    99 ISGGWLDGFFVLCASLSQNTAQLMAFKFFDGLIICGPFAVVVSYLAEFHGKKHRPYIMLFVGLCV 163
            :....::....:..:.|.|...::.|:...||:..|.:....:.:.||.|...|..:.:...:..
Human   180 LGTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMYQMAF 244

  Fly   164 SIGSMILPLLSYLLLPVPILFTVSSMKFRTWQVFLAVSSAPSLLSGFLHIFLPESPKFLMSQGNY 228
            ::|.:.|..|:|.|              ..|:......|.|:.|....:..:||||::|:||...
Human   245 TVGLVALTGLAYAL--------------PHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRN 295

  Fly   229 KKALDSLQRIYKLNKRKSRESYPIKHLTDPTPDRSDDLDGTGRPSTLQERFSRAQSKFIDGFKQ- 292
            .:|:..:..|.:.|.:           ..|.     ||........:.|:.|   ..|.|.|:.
Human   296 TEAIKIMDHIAQKNGK-----------LPPA-----DLKMLSLEEDVTEKLS---PSFADLFRTP 341

  Fly   293 --LKPMFSSPYL----AISLQVYCLHFCQIMCVNSVRLWLPQIFATMNAMDTLGANDTSMCAVLE 351
              .|..|...||    ::..|...||    |...|..|:|..:::
Human   342 RLRKRTFILMYLWFTDSVLYQGLILH----MGATSGNLYLDFLYS-------------------- 382

  Fly   352 HNANAKSMDEEEKRVECALHHDPDSYLNNITVAGIGLVGFLIIFPLMRFQVVSNHILKVFLFICI 416
                             ||...|.:::..||:..:|.     |:|:    .:||.:......:.|
Human   383 -----------------ALVEIPGAFIALITIDRVGR-----IYPM----AMSNLLAGAACLVMI 421

  Fly   417 FLVGSLYFVKTSLVTMMVSAVYLTMMGICATTIIGMSVVIFPTLMRTMVLLLIMTFGRLGSVSGN 481
            |:...|:::  :::.|.|..:.:|   |....|..::..::||.:|.:.:::..:...:|.:
Human   422 FISPDLHWL--NIIIMCVGRMGIT---IAIQMICLVNAELYPTFVRNLGVMVCSSLCDIGGI--- 478

  Fly   482 MLLPVFMQLSCLAPFL 497
                       :.||:
Human   479 -----------ITPFI 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14691	NP_650012.2	MFS	30..>216	CDD:119392	34/181 (19%)
SLC22A1	XP_005267159.1	2A0119	12..499	CDD:273328	87/471 (18%)
		MFS	118..484	CDD:119392	87/471 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153579
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.850