Protein Alignment CG14691 and SLC22A23

DIOPT Version :9

• Sequence 1: NP_650012.2
• Gene: CG14691 / 41287
• FlyBaseID: FBgn0037829
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: XP_011513103.1
• Gene: SLC22A23 / 63027
• HGNCID: 21106
• Length: 710
• Species: Homo sapiens
• Alignment Length: 495
• Identity: 107/495 - (21%)
• Similarity: 177/495 - (35%)
• Gaps: 114/495 - (23%)

  Fly    57 ECDLDLSIVDKGMLHAVTYA---GMIISAVPWGFIADTIGRRPVLISGGWLDGFFVLCASLSQNT 118
            |.:.||...:...:|...::   |:|...:..|.|||.:||||||:........|.|..:||.|.
Human   240 ELNWDLVCDNAWKVHIAKFSLLVGLIFGYLITGCIADWVGRRPVLLFSIIFILIFGLTVALSVNV 304

  Fly   119 AQLMAFKFFDGLIICGPFAVVVSYLAEFHGKKHRPYIMLFVGLCVSIGSMILPLLSYLLLPVPIL 183
            ......:||:|..:.|....:.:...|......|..|.:........|..::|.|:.|.
Human   305 TMFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFMITMVASFVAMAGQFLMPGLAALC------ 363

  Fly   184 FTVSSMKFRTWQVFLAVSSAPSLLSGFLHIFLPESPKFLMSQGNYKKALDSLQRIYKLNKRKSRE 248
                    |.|||..|:...|.||........|||.::||:...::.|           ||.
Human   364 --------RDWQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESA-----------KRL--- 406

  Fly   249 SYPIKHLTDPTPDRSDDLDGTGRPSTLQERFSRAQSKFIDGFKQLKPMFSSPYLAISLQVYCLHF 313
               |.|.|... ..:.:.|..|....|::..||...|                           .
Human   407 ---ILHFTQKN-RMNPEGDIKGVIPELEKELSRRPKK---------------------------V 440

  Fly   314 CQIMCVNSVRLWLPQIFATMNAMDTLGANDTSMCAVLEHNANAKSMDEEEKRVECALHHDPDSYL 378
            |.:..|.:..||...:...:|::...|.          |:..|:||...|.:|....:...|.|
Human   441 CIVKVVGTRNLWKNIVVLCVNSLTGYGI----------HHCFARSMMGHEVKVPLLENFYADYY- 494

  Fly   379 NNITVAGIGLVGFLIIFPLMRFQVVSNHILKVFLFICIFLVGSLYFVKTSLVTMMVS-------- 435
               |.|.|.||..|.:..::||......:|   ||:.:..:.||  ::..|:.::..
Human   495 ---TTASIALVSCLAMCVVVRFLGRRGGLL---LFMILTALASL--LQLGLLNLIGKYSQHPDSG 551

  Fly   436 ---------AVYLTMMGICATTIIGMSVVIF-----PTLMRTMVLLLIMTFGRLGSVSGNMLLPV 486
                     ::..:::|:.|:..:|...|.|     ||::|...|.|:     |.|....||...
Human   552 MSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTVIRCGGLGLV-----LASAGFGMLTAP 611

  Fly   487 FMQLS-----CLAPFLWLCSLMSIAFLFSLFLKVDDEQSL 521
            .::|.     .|...::.|..: |..:..|.|....:|:|
Human   612 IIELHNQKGYFLHHIIFACCTL-ICIICILLLPESRDQNL 650

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14691	NP_650012.2	MFS	30..>216	CDD:119392	40/161 (25%)
SLC22A23	XP_011513103.1	2A0119	<243..652	CDD:273328	106/492 (22%)
		MFS	259..>388	CDD:119392	36/142 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153276
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930