Protein Alignment CG14691 and Slc22a17

DIOPT Version :10

• Sequence 1: NP_650012.2
• Gene: CG14691 / 41287
• FlyBaseID: FBgn0037829
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_001347335.2
• Gene: Slc22a17 / 59049
• MGIID: 1926225
• Length: 627
• Species: Mus musculus
• Alignment Length: 512
• Identity: 101/512 - (19%)
• Similarity: 187/512 - (36%)
• Gaps: 115/512 - (22%)

  Fly    12 PADFETAIAECGFGLFNVFILCSAVPCLTAMVFSASALSYVMPSAECDLDLSIVDKGMLHAVTYA 76
            |.||...:.:..:         :.:|.||........|       .|||...::.:.:|..:.:|
Mouse   171 PPDFNHCLKDWDY---------NGLPVLTTNAIGQWDL-------VCDLGWQVILEQILFILGFA 219

  Fly    77 GMIISAVPWGFIADTIGRRPVLISGGWLDGFFVLCASLSQNTAQLMAFKFFDGLIICGPFAVVVS 141
            ...:..   |:.||..|||.:::....|.|...:..:.:.::..:||.:|..|.::.|....|..
Mouse   220 SGYLFL---GYPADRFGRRGIVLLTLGLVGPCGVGGAAAGSSTGIMALRFLLGFLLAGVDLGVYL 281

  Fly   142 YLAEFHGKKHRPYIMLFVGLCVSIGSMILPLLSYLLLPVPILFTVSSMKFRTWQVFLAVSSAPSL 206
            ...|......|..:.| .|..|.:|.             ..||...::..:.|:....:.:||.:
Mouse   282 MRLELCDPTQRLRVAL-AGELVGVGG-------------HFLFLGLALVSKDWRFLQRMITAPCI 332

  Fly   207 L---SGFLHIFLPESPKFLMSQGNYKKALDSLQRIYKLNKRKSRESYPIKHLTDPTPDRSDDLDG 268
            |   .|:..:|| ||.::|:    .|:.::..|.:.::...::|....:  |.:...:...:|:.
Mouse   333 LFLFYGWPGLFL-ESARWLI----VKRQIEEAQSVLRILAERNRPHGQM--LGEEAQEALQELEN 390

  Fly   269 TGRPSTLQERFSRAQSKFIDGFKQLKPMFSS--PYLAISLQVYCLHFCQIMCVNSVRLWLPQIFA 331
            | .|......||                |:|  .|..|...:..|.|...:.           .|
Mouse   391 T-CPLPATSTFS----------------FASLLNYRNIWKNLLILGFTNFIA-----------HA 427

  Fly   332 TMNAMDTLGA----NDTSMCAVLEHNANAKSMDEEEKRVECALHHDPDSYLNNITVAGIGLVGFL 392
            ..:....:|.    :|..:|::|.....|         :.|.       :| .:||...|..|.|
Mouse   428 IRHCYQPVGGGGSPSDFYLCSLLASGTAA---------LACV-------FL-GVTVDRFGRRGIL 475

  Fly   393 IIFPLMRFQVVSNHILKVFLFICIFLVGSL-YFVKTSLVTMMVSAVYLTMMGICATTIIGMSVVI 456
            ::  .|....:::          :.|:|.. |....::.|..|..::.:......:|::...|:
Mouse   476 LL--SMTLTGIAS----------LVLLGLWDYLNDAAITTFSVLGLFSSQASAILSTLLASEVI- 527

  Fly   457 FPTLMRTMVLLLIMTFGRLGSVSG-----NMLLPVFMQLSCLAPFLWLCSLMSIAFL 508
             ||.:|...|.|||..|.||.:|.     :|....|:|...||....|| ::||..|
Mouse   528 -PTTVRGRGLGLIMALGALGGLSCPAQRLHMGHGAFLQHVVLAACALLC-ILSIMLL 582

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14691	NP_650012.2	synapt_SV2	2..>337	CDD:130366	60/329 (18%)
		MFS	<375..513	CDD:475125	35/140 (25%)
Slc22a17	NP_001347335.2	MFS_SLC22A17	170..583	CDD:341003	101/512 (20%)