Protein Alignment CG14691 and sv2

DIOPT Version :10

• Sequence 1: NP_650012.2
• Gene: CG14691 / 41287
• FlyBaseID: FBgn0037829
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: XP_009296040.2
• Gene: sv2 / 570651
• ZFINID: ZDB-GENE-000607-80
• Length: 522
• Species: Danio rerio
• Alignment Length: 536
• Identity: 155/536 - (28%)
• Similarity: 253/536 - (47%)
• Gaps: 70/536 - (13%)

  Fly     7 DNTDEPAD------FETAIAECGFGLFNVFILCSAVPCLTAMVFSA---SALSYVMPSAECDLDL 62
            :..||.|.      :|.|:.:.|||||:..:|   |.|..|....|   ..:|:::|:|.|||.|
Zfish    19 EEDDEQASCRKKLTYEEAVEKAGFGLFHWLLL---VVCGWANASDAVEILCVSFLLPTARCDLQL 80

  Fly    63 SIVDKGMLHAVTYAGMIISAVPWGFIADTIGRRPVLISGGWLDGFFVLCASLSQNTAQLMAFKFF 127
            |..|.|:|.|..:.||::....|||:||..|||.||:....::|.|...|||:......:..:||
Zfish    81 SSADMGILTASIFLGMMVGGCVWGFLADRRGRRSVLVVSLAVNGTFGAVASLAPAFWLFLLLRFF 145

  Fly   128 DGLIICGPFAVVVSYLAEFHGKKHRPYIMLFVGLCVSIGSMILPL-------------LSYLLLP 179
            .|:.:.|...|:.||.:||     :|        |:..|:||..|             :::|::|
Zfish   146 SGVGVGGSIPVIFSYFSEF-----QP--------CLRRGAMISALATFWMAGNILAAGVAWLVIP 197

  Fly   180 -VPILFTVSSMKFRTWQVFLAVSSAPSLLSGFL-HIFLPESPKFLMSQGNYKKALDSLQRIYKLN 242
             ..:......:.|::|::|:.:.|.|||.|..: .:|:||||||||..|...:||...|:|||||
Zfish   198 RTSLNADWGWLDFQSWRLFVVLCSIPSLSSALIFRLFMPESPKFLMEAGREMEALTVFQKIYKLN 262

  Fly   243 KRKSRESYPIKHLTDPTPDRSDDLDGTGRPSTLQERFSRAQSKFIDGFKQLKPMFSSPYLAISLQ 307
            .|.:.:.:|:..|.    .|..|.:...|||....|..|..::.......||.:|..|..:.|:.
Zfish   263 NRGATKPFPVSGLM----IRPKDDEVKNRPSHSSSRSQRFINQLTQALVPLKQLFVRPLASRSVV 323

  Fly   308 VYCLHFCQIMCVNSVRLWLPQIFATMNAMDTLGAND-TSMCAVLEHNANAKSMDEEEK--RVECA 369
            :..:.||.......:.:|.|::|..        |.| .|.||.:....||    |.||  .|:.|
Zfish   324 LVIIFFCISFGYYGLWMWFPELFKR--------AEDGGSPCANMSRAQNA----ENEKCYPVKTA 376

  Fly   370 LHHDPDSYLNNITVAGIGLVGFLIIFPLMRFQVVSNHILKVFLFICIFLVGSLYFVKTSLVTMMV 434
            :      |:.....|...|.|.:....||. ::....:|.|.|.:....|..:|.|||...:::|
Zfish   377 V------YMEGFITAASNLPGNIFTILLMD-RIGGKILLSVSLLVSGVSVFVIYVVKTKTQSLIV 434

  Fly   435 SAVY--LTMMGICATTIIGMSVVIFPTLMRTMVLLLIMTFGRLGSVSGNMLLPVFMQLSCLAPFL 497
            |.|:  ::::...|..::|..  ::||.:|:..|.:....||:.::.||::....:..||..|.|
Zfish   435 SCVFSGVSVISWNALDVVGTE--LYPTQLRSSALGVFTGVGRVAAIMGNVVFGQLVDSSCAVPLL 497

  Fly   498 WLCSLMSIAFLFSLFL 513
            .:|.|:....|.:|:|
Zfish   498 MVCVLLLAGGLAALWL 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14691	NP_650012.2	synapt_SV2	2..>337	CDD:130366	107/353 (30%)
		MFS	<375..513	CDD:475125	35/139 (25%)
sv2	XP_009296040.2	None