DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG14691 and Slc22a21

DIOPT Version :9

Sequence 1:NP_650012.2 Gene:CG14691 / 41287 FlyBaseID:FBgn0037829 Length:522 Species:Drosophila melanogaster
Sequence 2:NP_062697.1 Gene:Slc22a21 / 56517 MGIID:1929481 Length:564 Species:Mus musculus


Alignment Length:482 Identity:104/482 - (21%)
Similarity:190/482 - (39%) Gaps:146/482 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    75 YAGMIISAVPWGFIADTIGRRPVL-ISGGWLDGF-FVLCASLSQNTAQLMAFKFFDGLIICGPFA 137
            |.|:::.:...|.::|..||:.:| ::.....|| |:...|::        |:.|..|.......
Mouse   150 YVGVLLGSFISGQLSDRFGRKNILFLTMAMHTGFSFIQVFSVN--------FEMFTLLYTLVGMG 206

  Fly   138 VVVSYLA------EFHGKKHRPYIMLFVGLCV--SIGSMILPLLSYLLLPVPILFTVSSMKFRTW 194
            .:.:|:|      |...|..| .|...:|:|:  :.|.|:|||.:|.:              |.|
Mouse   207 HISNYVAAFVLGTEMLSKSVR-IIFATLGVCIFFAFGFMVLPLFAYFI--------------REW 256

  Fly   195 QVFLAVSSAPSLLSGFLHIFLPESPKFLMSQGNYKKALDSLQRIYKLNKRKSRESYPIKHLTDPT 259
            :..|...:.|.:|.|.|..|:||||::|:|||..|:|...:::..|:|                 
Mouse   257 RRLLLAITLPGVLCGALWWFIPESPRWLISQGRIKEAEVIIRKAAKIN----------------- 304

  Fly   260 PDRSDDLDGTGRPSTLQERFSRAQSKFIDGFKQLKPMFSSPYLAISLQVYCL---HFCQIMCVNS 321
                    |...|||:   |..:::..:......||.        |..:|.|   ...:|:.:.|
Mouse   305 --------GIVAPSTI---FDPSETNKLQDDSSKKPQ--------SHHIYDLVRTPNIRILTIMS 350

  Fly   322 VRLWLPQIFATMN------AMDTLGANDTSMCAVLEHNANAKSMDEEEKRVECALHHDPDSYLNN 380
            :.|||     |::      ::||...|.                               :.|:|.
Mouse   351 IILWL-----TISVGYFGLSLDTPNLNG-------------------------------NIYVNC 379

  Fly   381 ITVAGIGLVGFLIIFPLM-----RFQVVSNHILKVFLFICIFLVGS-LYFVKTSLV-------TM 432
            ..:|.:.:..:::.:.|:     |:.:..:..|...:.:.:.||.| |:::.|:||       |.
Mouse   380 FLLAAVEVPAYVLAWLLLQHVSRRYSMAGSLFLGGSVLLLVQLVPSDLHYLSTTLVMVGKFGITS 444

  Fly   433 MVSAVYLTMMGICATTIIGMSVVIFPTLMRTMVLLLIMTFGRLGSVSGNMLLPVFMQLSCL---A 494
            ..|.||:            .:..::||::|.|.:.:..|..||||:    |.|.|:.|...   .
Mouse   445 AYSMVYV------------YTAELYPTVVRNMGVGVSSTASRLGSI----LSPYFVYLGAYDRRL 493

  Fly   495 PFLWLCSLMSIAFLFSLFLKVDDEQSL 521
            |::.:.||..:..:.:||.......||
Mouse   494 PYILMGSLTILTAIITLFFPESSGVSL 520

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG14691NP_650012.2 MFS 30..>216 CDD:119392 36/150 (24%)
Slc22a21NP_062697.1 2A0119 12..523 CDD:273328 104/482 (22%)
MFS 123..513 CDD:119392 102/473 (22%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 532..564
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167843725
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG57756
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
43.850

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