Protein Alignment CG14691 and Slc22a28

DIOPT Version :10

• Sequence 1: NP_650012.2
• Gene: CG14691 / 41287
• FlyBaseID: FBgn0037829
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_001013842.2
• Gene: Slc22a28 / 434674
• MGIID: 3645714
• Length: 552
• Species: Mus musculus
• Alignment Length: 499
• Identity: 98/499 - (19%)
• Similarity: 185/499 - (37%)
• Gaps: 121/499 - (24%)

  Fly    37 PCLTAMVFSAS-ALSYVMPSAECDLDLSIVDKGMLHAVT----YAGMIISAVPWGFIADTIGRRP 96
            ||:...|:..| .||.::  .|.||   :.:...|::|.    ..|:.|.|:..|.::|..||:.
Mouse   115 PCVDGWVYDRSNFLSTIV--TEWDL---VCESQALNSVAKFSFMIGLFIGAIICGHLSDRFGRKF 174

  Fly    97 VLISG-----------GWLDGFFVLCASLSQNTAQLMAFKFFDGLIICGPFAVVVSYL-AEFHGK 149
            :|...           .:...||:.|           ..:|..|:.: .|.:|..:.| .|:...
Mouse   175 ILTCALLQFAITETCVAFAPSFFIYC-----------LLRFLAGMSV-EPISVNSNLLILEWTNP 227

  Fly   150 KHRPYIMLFVGLCVSIGSMILPLLSYLLLPVPILFTVSSMKFRTWQVFLAVSSAPSLLSGFLHIF 214
            |....:.:......|||.|||..|::|              ||.|.......|.|......|..:
Mouse   228 KFLGMVAVLTSCAASIGYMILAGLAFL--------------FRIWHHLQLAMSVPIFFFFILTRW 278

  Fly   215 LPESPKFLMSQGNYKKALDSLQRIYKLNKRKSRESYPIKHLTDPTPDRSDDLDGTGRPSTLQERF 279
            :.||.::|:.....:|.|..|:::..:|..|:..:.....:.:.:  ..::|:...|.|:.::.|
Mouse   279 MSESARWLIVTNKPQKGLKELRKVAHMNGMKNSGNTLTMEVVEAS--MKNELEAAKRKSSPRDLF 341

  Fly   280 SRAQSKFIDGFKQLKPMFSSPYLAISLQVYCLHFCQIMCVNSVRLWLPQIFATMNAMDTLGANDT 344
            .             .|:..:....:|...|              |:...||.....:..|..|..
Mouse   342 H-------------TPILRNRICVLSFMRY--------------LFTVSIFGLSLHLQHLSTNII 379

  Fly   345 SMCAVLEHNANAKSMDEEEKRVECALHHDPDSYLNNITVAGIGLVGFLIIFPLMR--FQVVSNHI 407
            .:                             .:|::.....|.::|..::..:.|  .|:|...:
Mouse   380 LL-----------------------------RFLSSALGILISVIGHFVLNHMGRRITQLVLMSL 415

  Fly   408 LKVFLFICIFLVGSLYFVKTSLVTMMVSAVYLTMMGICATTI-IGMSVVIFPTLMRTMVLLLIMT 471
            ..:|:...:|:...:..::..:||:   |..|:.:.:|.:.: |.   .:.||.:|...:.:|..
Mouse   416 RGIFMLTAVFVPQEMQTLRIIVVTL---AAALSSLCMCVSNLHIN---ELLPTTLRATGMGVIGM 474

  Fly   472 FGRLGSVSGNMLLPVFMQLSCLAPFL-WL-CSLMSIAFLFSLFL 513
            ||.    ||..|.|:||.|:..:..| |: ....||.:.||:||
Mouse   475 FGN----SGLFLAPLFMLLATYSANLPWIFYGGFSILYGFSVFL 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14691	NP_650012.2	synapt_SV2	2..>337	CDD:130366	61/316 (19%)
		MFS	<375..513	CDD:475125	33/142 (23%)
Slc22a28	NP_001013842.2	MFS_OAT	109..516	CDD:340932	98/499 (20%)