Protein Alignment CG14691 and SLC22A

DIOPT Version :10

• Sequence 1: NP_650012.2
• Gene: CG14691 / 41287
• FlyBaseID: FBgn0037829
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Alignment Length: 615
• Identity: 120/615 - (19%)
• Similarity: 194/615 - (31%)
• Gaps: 204/615 - (33%)

  Fly     1 MADRAKDNTDEPADFETAIAECG-FGLFN--VFILCSAVPCLTAMVFSASALSYVMPSA------ 56
            :|..|||:.|...|  ..:...| ||.|.  :|:|.    ||..|..:..:::||..:|
  Fly    15 VAPPAKDSEDVTLD--AILKHLGQFGRFQLIIFLLI----CLPMMFHAMFSVTYVFTAATVTHRC 73

  Fly    57 ---ECDL---------------------------------------DLSIVDK------------ 67
               ||||                                       |:...|.
  Fly    74 SVEECDLPGSNYYEPHTNWSIPKNGKDLDSCNRYTNSELPQWNHSVDICSADHFTKNKEACAHNE 138

  Fly    68 ------------------------GMLHAVTYAGMIISAVPWGFIADTIGRRPVLISGGWLDGFF 108
                                    .|:..:...|........||:||..||...:..||.|....
  Fly   139 FVFRDDEVTISNDFGIFCDDEWKLSMVGTINNLGQFFGIPIGGFVADRYGRSFSIALGGILGAVL 203

  Fly   109 VLCASLSQNTAQLMAFKFFDGLIICGPFAVVVSYLAEFHGKKHRPYIMLFVGLCVSIGSMILPLL 173
            .:..|.|.:....:.|:|.|.:.....::.......|..|.|.|......:.:..::|.
  Fly   204 GVIRSFSPSYGWFLVFEFLDNMTSSTLYSTCFVIGIELVGPKRRVLACSVITVFYAVGE------ 262

  Fly   174 SYLLLPVPILFTVSSMKFRTWQVFLAVSSAPSLLSGFLHIFLPESPKFLMSQGNYKKALDSLQRI 238
                    :|..:|:..|..|::.|.::..|||:.......||||.::|:|||..::|.:.|:|.
  Fly   263 --------VLLAMSAKAFHDWRILLRITYGPSLILLAYFWILPESVRWLLSQGKEERAKNILRRA 319

  Fly   239 YKLNKRKSRESYPIKHLTDPTPDRSDDLDGTGRPSTLQERFSRAQSKFIDGFKQLKPMFSS---- 299
            ..:|||:..||.            .|.|....|....|...||...:  :.||..|...::
  Fly   320 AHVNKRELPESV------------LDKLVLANRDKLQQSSESRFPIR--EAFKNFKWRIANCSLC 370

  Fly   300 ------PYLAISLQVYCL------HFCQIMCVNSVRLWLPQIFATMNAMDTLGANDTSMCAVLEH 352
                  .|..:||.|..|      :|..|..|.     :|..|..:..||..|.. .|:|.::
  Fly   371 WIVHVLVYYGLSLNVVLLDGDKYNNFAYIALVE-----IPGFFMPLLIMDRFGRR-YSLCGLM-- 427

  Fly   353 NANAKSMDEEEKRVECALHHDPDSYLNNITVAGIGLVGFLIIFPLMRFQVVSNHILKVFLFICIF 417
                                         ..:|:..:|.:       |......:|::.|    |
  Fly   428 -----------------------------LASGLCCIGTI-------FTGADQPVLQLVL----F 452

  Fly   418 LVGSLYFVKTSLVTMMVSAVYLTMMGICATTIIGMSVVIFPTLMRTMVLLLIMTFGRLGSVSGNM 482
            |||.|      .:|.....:|.            .:..|:||.:|..:|......||.||:....
  Fly   453 LVGKL------TITASFQVLYF------------FASEIYPTNLRNSLLSFCSMMGRFGSMLAPQ 499

  Fly   483 LLPVFMQLSCLAPFLWLCSLMSIAFLFSLF 512
             .|:..:....||.:.......::.|.:||
  Fly   500 -TPLLAKYYANAPAMLFAGAAIVSGLLTLF 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14691	NP_650012.2	synapt_SV2	2..>337	CDD:130366	88/437 (20%)
		MFS	<375..513	CDD:475125	27/138 (20%)
SLC22A	NP_649370.1	MFS_SLC22	136..530	CDD:340875	96/488 (20%)