Protein Alignment CG14691 and SLC22A25

DIOPT Version :9

• Sequence 1: NP_650012.2
• Gene: CG14691 / 41287
• FlyBaseID: FBgn0037829
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: XP_016873173.1
• Gene: SLC22A25 / 387601
• HGNCID: 32935
• Length: 577
• Species: Homo sapiens
• Alignment Length: 563
• Identity: 107/563 - (19%)
• Similarity: 179/563 - (31%)
• Gaps: 211/563 - (37%)

  Fly     8 NTDEPADFETAIAECGFGLFNVFILCSAVPCLTAMVFSASALSYVMPS---AECDLDLSIVDKGM 69
            ||.|| |.|                    ||:...|:..|:    .||   .:.||   :.:...
Human   107 NTSEP-DTE--------------------PCVDGWVYDQSS----FPSTIVTKWDL---VCESQP 143

  Fly    70 LHAVT----YAGMIISAVPWGFIADTIGRRPVLISGG---------------------WLDGFFV 109
            |::|.    .|||::....:|.::|   |:|:.....                     |....||
Human   144 LNSVAKFLFMAGMMVGGNLYGHLSD---RKPLSSPNHVSTDCDEGLEVPIAIHQHHVFWFGRKFV 205

  Fly   110 L------------CASLSQNTAQLMAFKFFDGL----IICGPFAVVVSYLAEFHGKKHRPYIM-L 157
            |            ||:.:.......:.:|..|.    ||.....::|.::.      |:...| |
Human   206 LRWSYLQLAIVGTCAAFAPTILVYCSLRFLAGAATFSIIVNTVLLIVEWIT------HQFCAMAL 264

  Fly   158 FVGLC-VSIGSMILPLLSYLLLPVPILFTVSSMKFRTWQVFLAVSSAPSLLSGFLHIFLPESPKF 221
            .:.|| .|||.:.|..|::::              |...:...|.|||..:......:|.||.::
Human   265 TLTLCAASIGHITLGSLAFVI--------------RDQCILQLVMSAPCFVFFLFSRWLAESARW 315

  Fly   222 LMSQGNYKKALDSLQRIYKLNKRKSRESYPIKHLTDPTPDRSDDLDGTGRPSTLQERFSRAQSKF 286
            |:.....::.|..|::....|..|:.|               |.|......||:::....||.|
Human   316 LIINNKPEEGLKELRKAAHRNGMKNAE---------------DILTMEVLKSTMKQELEAAQKK- 364

  Fly   287 IDGFKQLKPMFSSPYLAISLQVYCLHFCQIMCV---NSVRLW---------------LPQIFATM 333
                ..|..:...|.:       |...|.:..|   :::..|               |..:|..:
Human   365 ----HSLCELLRIPNI-------CKRICFLSFVRFASTIPFWGLTLHLQHLGNNVFLLQTLFGAV 418

  Fly   334 NAMDTLGANDTSMCAVLEHNANAKSMDEEEKRVECALHHDPDSYLNNITVAGIGLVGFLIIFPLM 398
                ||.||..:..| |.|.:...|.                               .|::|
Human   419 ----TLLANCVAPWA-LNHMSRRLSQ-------------------------------MLLMF--- 444

  Fly   399 RFQVVSNHILKVFLFICIFLVGSLYFVKTSLVTMMVSAVYLTMMGICATTIIGMSVVIFPTLMRT 463
                    :|...|...||:...:..::..|.|:.|.|..|   ||..:|  .....:.|:::|
Human   445 --------LLATCLLAIIFVPQEMQTLRVVLATLGVGAASL---GITCST--AQENELIPSIIR- 495

  Fly   464 MVLLLIMTFGRLGSVSGNM------LLPVFMQLSCLA-PFLWL 499
                     ||...::||.      |..:.|.||..: |..|:
Human   496 ---------GRATGITGNFANIGGALASLMMILSIYSRPLPWI 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14691	NP_650012.2	MFS	30..>216	CDD:119392	43/231 (19%)
SLC22A25	XP_016873173.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153567
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840