Protein Alignment CG14691 and Slc22a30

DIOPT Version :10

• Sequence 1: NP_650012.2
• Gene: CG14691 / 41287
• FlyBaseID: FBgn0037829
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_795976.1
• Gene: Slc22a30 / 319800
• MGIID: 2442750
• Length: 552
• Species: Mus musculus
• Alignment Length: 501
• Identity: 100/501 - (19%)
• Similarity: 186/501 - (37%)
• Gaps: 125/501 - (24%)

  Fly    37 PCLTAMVFSAS-ALSYVMPSAECDLDLSIVDKGMLHAVT----YAGMIISAVPWGFIADTIGRRP 96
            ||:...|:..| .||.::  .|.||   :.:...|::|.    ..|:.|.|:..|.::|..||:.
Mouse   115 PCVDGWVYDRSNFLSTIV--TEWDL---VCESQALNSVAKFSFMIGLFIGAIICGHLSDRFGRKF 174

  Fly    97 VLISG-----------GWLDGFFVLCASLSQNTAQLMAFKFFDGLIICGPFAVVVSYL-AEFHGK 149
            :|...           .:...||:.|           ..:|..|:.: .|.:|....| .|:...
Mouse   175 ILTCALLQFAITETCVAFAPSFFIYC-----------LLRFLAGMSV-EPISVNSHLLMLEWTSP 227

  Fly   150 KHRPYIMLFVGLCVSIGSMILPLLSYLLLPVPILFTVSSMKFRTWQVFLAVSSAPSLLSGFLHIF 214
            |....:.:......|||.|||..|::|              ||.|:......|.|......|..:
Mouse   228 KFLGMVAVLTSCAASIGYMILAGLAFL--------------FRIWRHLQLAMSVPIFFFLILTRW 278

  Fly   215 LPESPKFLMSQGNYKKALDSLQRIYKLNKRKSRESYPIKHLTDPTPDRSDDLDGTGRPSTLQERF 279
            :.||.::|:.....:|.|..|:::..:|..|:..:.....:.:.:  ..::|:...|.|:.::
Mouse   279 MSESARWLIVTNKPQKGLKELRKVAHMNGMKNSGNTLTMEVVEAS--MKNELEAAKRKSSPRD-- 339

  Fly   280 SRAQSKFIDGFKQLKPMFSSPYLAISLQVYCLHFCQIMCVNSVR--LWLPQIFATMNAMDTLGAN 342
                            :|.:|.|.           :.:||.|..  |:...||.....:..|..|
Mouse   340 ----------------LFHTPILR-----------KRICVLSFMRYLFTISIFGLSLHLQHLSTN 377

  Fly   343 DTSMCAVLEHNANAKSMDEEEKRVECALHHDPDSYLNNITVAGIGLVGFLIIFPLMR--FQVVSN 405
            ...:                             .:|::.....|.::|..::..:.|  .|:|..
Mouse   378 IILL-----------------------------QFLSSALGILISVIGHFVLNHMGRRITQLVLM 413

  Fly   406 HILKVFLFICIFLVGSLYFVKTSLVTMMVSAVYLTMMGICATTI-IGMSVVIFPTLMRTMVLLLI 469
            .:..:|:...:|:...:   :|..:.|...|..|:.:.:|.:.: |.   .:.||.:|...:.:|
Mouse   414 SLRGIFMLTAVFVPQEM---QTLRIIMATLAAALSSLCMCVSNLHIN---ELLPTTLRATGMGVI 472

  Fly   470 MTFGRLGSVSGNMLLPVFMQLSCLAPFL-WL-CSLMSIAFLFSLFL 513
            ..||.    ||..|.|:||.|:..:..| |: ....||.:.||:||
Mouse   473 AMFGN----SGLFLAPLFMLLATYSANLPWIFYGGFSILYGFSVFL 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14691	NP_650012.2	synapt_SV2	2..>337	CDD:130366	63/318 (20%)
		MFS	<375..513	CDD:475125	33/142 (23%)
Slc22a30	NP_795976.1	MFS_OAT	109..516	CDD:340932	100/501 (20%)