Protein Alignment CG14691 and Slc22a15

DIOPT Version :10

• Sequence 1: NP_650012.2
• Gene: CG14691 / 41287
• FlyBaseID: FBgn0037829
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_001101177.1
• Gene: Slc22a15 / 310732
• RGDID: 1311184
• Length: 548
• Species: Rattus norvegicus
• Alignment Length: 448
• Identity: 99/448 - (22%)
• Similarity: 168/448 - (37%)
• Gaps: 99/448 - (22%)

  Fly    75 YAGMIISAVPWGFIADTIGRRPVLISGGWLDGFFVLCASLSQNTAQLMAFKFFDGLIICGPFAVV 139
            ::|:.:..:.:|.::|..||:.|.::|..||..|.:....|.:.......:|..|::..|...|.
  Rat   119 FSGVFVGVISFGQLSDRFGRKKVYLTGFALDILFAIANGFSPSYEFFAVTRFLVGMMNGGMSLVA 183

  Fly   140 VSYLAEFHGKKHRPYIMLFVGLCVSIGSMILPLLSYLLLPVPILFTVSSMKFRTWQVFLAVSSAP 204
            ...|.|..|..:........||..::|.....||.|.:              |:|:....:.:..
  Rat   184 FVLLNECVGAAYWALAGSIGGLFFAVGIAQYALLGYFI--------------RSWRTLAILVNLQ 234

  Fly   205 SLLSGFLHIFLPESPKFLMSQGNYKKALDSLQRIYKLNKRKSRESYPIKHLTDPTPDRSDDLDGT 269
            ..:...|.:|:||||::|.|||...:|.::|..|.|.| ||.:.::.:.|
  Rat   235 GTVVFLLSLFIPESPRWLYSQGRLSEAEEALYLIAKRN-RKLKCTFSLTH--------------- 283

  Fly   270 GRPSTLQERFSRAQSKFIDGFKQLKPMFSSPYLAISLQVYCLHFCQIMCVNSVRLWLPQIFATMN 334
              |:   .|..|....|:|.|:         |..:......|.|...:|.      |.....|::
  Rat   284 --PA---NRSYRETGSFLDLFR---------YRVLLGHTLILMFIWFVCS------LVYYGLTLS 328

  Fly   335 AMDTLGANDTSMCAVLEHNANAKSMDEEEKRVECALHHDPDSYLNN-------ITVAGI----GL 388
            |.|..|:        :..|.....:.|......|.       ||.|       .|:|..    ||
  Rat   329 AGDLGGS--------IYANLALSGLIEIPSYPLCI-------YLINQRWFGRKRTLAAFLCLGGL 378

  Fly   389 VGFLIIF-PLMR----FQVVSNHILKVFLFICIFLVGSLYF-VKTSLVTMMVSAVYLTM-----M 442
            ...:::| |..:    |.||::|.|.        |:|.|.. ...::|.:..|.:|.|:     :
  Rat   379 ACLIVMFLPEKKDTGVFAVVNSHSLS--------LLGKLTISAAFNIVYIYTSELYPTVIRNVGL 435

  Fly   443 GICA--TTIIGMSVVIFPTLMRTMVLLLIMTFGRLGSVSG--NMLLPVFMQLSCLAPF 496
            |.|:  :.:.|:.....|:|......|..:.||..|..||  ::|||..:....|..|
  Rat   436 GTCSMFSRVGGIIAPFVPSLKDVQWSLPFIVFGATGLTSGLLSLLLPETLNSPLLETF 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14691	NP_650012.2	synapt_SV2	2..>337	CDD:130366	57/261 (22%)
		MFS	<375..513	CDD:475125	37/148 (25%)
Slc22a15	NP_001101177.1	MFS_SLC22A15	71..469	CDD:340935	90/422 (21%)