DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14691 and Slc22a22

DIOPT Version :9

Sequence 1:	NP_650012.2	Gene:	CG14691 / 41287	FlyBaseID:	FBgn0037829	Length:	522	Species:	Drosophila melanogaster
Sequence 2:	NP_001013969.1	Gene:	Slc22a22 / 299944	RGDID:	1304605	Length:	555	Species:	Rattus norvegicus

Alignment Length:	498	Identity:	98/498 - (19%)
Similarity:	178/498 - (35%)	Gaps:	121/498 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 PCLTAMVFSASALSYVMPSAECDLDLSIVD----KGMLHAVTYAGMIISAVPWGFIADTIGRRPV 97
            |||....:..|..:..:.: |.||   :.|    |....|.:.||..::|...|.|:|..||:|:
  Rat   115 PCLDGWTYDHSVFTSTIVT-EWDL---VCDFQSFKYYAQATSLAGHFVAAPFCGIISDRFGRKPL 175

  Fly    98 LISGGWLDGFFVLCASLSQNTAQLMAFKFFDGL------IICGPFAVVVSYLAEFHGKKHRPYIM 156
            |:......|....|.:...|.:.....:|....      :.|     ::..|.|...:.|...|:
  Rat   176 LMYCSLAYGILGTCCAFVPNFSLYCVLRFLSSASASTVGMNC-----LILVLEETSVQWHATVIV 235

  Fly   157 LFVGLCVSIGSMILPLLSYLLLPVPILFTVSSMKFRTWQVFLAVSSAPSLLSGFLHIFLPESPKF 221
            | .||..|.|...|..|:|:|              ..|.:....|:.|..:...|..::|||.::
  Rat   236 L-SGLFSSTGLAGLGGLAYVL--------------SDWHLIQLTSALPYFIFFILFCWVPESARW 285

  Fly   222 LMSQGNYKKALDSLQRIYKLNKRKSRESYPIKHLTDPTPDRSDDLDGTGRPSTLQERFSRAQSKF 286
            ||..|...:||..||||..:|.:|               |.:.:|......|.::|........|
  Rat   286 LMITGKTDQALKELQRIASINGKK---------------DIAQNLTTEDLRSKVKEDVCSTVKHF 335

  Fly   287 IDGFKQLKPMFSSPYLAISLQVYCLHFCQIMCVNSVRL-WLPQIFATMNAMDTLGANDTSMCAVL 350
                 .:|.:..:|.:...          ::|.:||.. .|..||..:..:..||.|
  Rat   336 -----SIKDIIINPMIRKI----------VLCYSSVLFAELFSIFGLLLDVHMLGKN-------- 377

  Fly   351 EHNANAKSMDEEEKRVECALHHDPDSYLNNITVAGIGLVGFLIIFPLMRFQVVSNHILKVFLF-- 413
                                     .::..|.:..|.:....:.:.::| .|....::...||
  Rat   378 -------------------------IFVTQILLGVIDIPSKSLTYFILR-NVRRRPLIAFLLFAT 416

  Fly   414 -----ICIFLVGSLYFVKTSLVTMMVSAVYLTMMGICATTIIGMSVV----IFPTLMRTMVLLLI 469
                 |.:||...:|.::.        |:::...| |....|.::..    :.|..:|:.:..:.
  Rat   417 GGCITITMFLSEDMYVLRL--------AIFILGKG-CFAAFISINTAYCNELSPVPLRSTLNGIY 472

  Fly   470 MTFGRLGSVSGNMLLPVFMQLSCLAPFLWLCSLMSIAFLFSLF 512
            ::..||.||...:.| |..:...|.|.:: |.::.|....:::
  Rat   473 ISVARLASVLSALTL-VTRKYFVLLPMIF-CGVLPIVATINIY 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14691	NP_650012.2	MFS	30..>216	CDD:119392	42/188 (22%)
Slc22a22	NP_001013969.1	2A0119	11..526	CDD:273328	98/498 (20%)
Slc22a22	NP_001013969.1	MFS	127..516	CDD:119392	94/486 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166347184
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840