DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG14691 and Slc22a5

DIOPT Version :9

Sequence 1:NP_650012.2 Gene:CG14691 / 41287 FlyBaseID:FBgn0037829 Length:522 Species:Drosophila melanogaster
Sequence 2:NP_062142.1 Gene:Slc22a5 / 29726 RGDID:3702 Length:557 Species:Rattus norvegicus


Alignment Length:469 Identity:107/469 - (22%)
Similarity:188/469 - (40%) Gaps:141/469 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    75 YAGMIISAVPWGFIADTIGRRPVL-ISGGWLDGFFVLCASLSQNTAQLMA--FKFFDGLIICGPF 136
            :.|:::.:...|.::|..||:.|| ::.|...||..|         ||.:  |:.|..|.:....
  Rat   150 FVGVLMGSFISGQLSDRFGRKNVLFLTMGMQTGFSFL---------QLFSVNFEMFTVLFVLVGM 205

  Fly   137 AVVVSYLA------EFHGKKHRPYIMLFVGLCV--SIGSMILPLLSYLLLPVPILFTVSSMKFRT 193
            ..:.:|:|      |...|..| .|...:|:|:  :.|.|:|||.:|.:              |.
  Rat   206 GQISNYVAAFVLGTEILSKSIR-IIFATLGVCIFYAFGFMVLPLFAYFI--------------RD 255

  Fly   194 WQVFLAVSSAPSLLSGFLHIFLPESPKFLMSQGNYKKALDSLQRIYKLNKRKSRESYPIKHLTDP 258
            |::.|...:.|.:|.|.|..|:||||::|:|||..|:|...:::..|.|                
  Rat   256 WRMLLLALTVPGVLCGALWWFIPESPRWLISQGRVKEAEVIIRKAAKFN---------------- 304

  Fly   259 TPDRSDDLDGTGRPSTLQERFSRAQSKFIDGFKQLKPMFSSPYLAISLQVYCL---HFCQIMCVN 320
                     |...|||:   |..::   :......||.        |..:|.|   ...:|:.:.
  Rat   305 ---------GIVAPSTI---FDPSE---LQDLNSKKPQ--------SHHIYDLVRTRNIRIITIM 346

  Fly   321 SVRLWLPQIFATMNAMDTLGANDTSMCAVLEHNANAKSMDEEEKRVECALHHDPDSYLNNITVAG 385
            |:.|||           |:......:           |:|...      ||  .|.|:|...:|.
  Rat   347 SIILWL-----------TISVGYFGL-----------SLDTPN------LH--GDIYVNCFLLAA 381

  Fly   386 IGLVGFLIIFPLM-----RFQVVSNHIL--KVFLFICIFLVGSLYFVKTSLV-------TMMVSA 436
            :.:..:::.:.|:     |:.:.:...|  .|.|||.: :...|:::.|:||       |...|.
  Rat   382 VEVPAYVLAWLLLQHLPRRYSISAALFLGGSVLLFIQL-VPSELFYLSTALVMVGKFGITSAYSM 445

  Fly   437 VYLTMMGICATTIIGMSVVIFPTLMRTMVLLLIMTFGRLGSVSGNMLLPVFMQLSC---LAPFLW 498
            ||:            .:..::||::|.|.:.:..|..||||:    |.|.|:.|..   ..|::.
  Rat   446 VYV------------YTAELYPTVVRNMGVGVSSTASRLGSI----LSPYFVYLGAYDRFLPYIL 494

  Fly   499 LCSLMSIAFLFSLF 512
            :.||..:..:.:||
  Rat   495 MGSLTILTAILTLF 508

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG14691NP_650012.2 MFS 30..>216 CDD:119392 38/151 (25%)
Slc22a5NP_062142.1 2A0119 12..520 CDD:273328 107/469 (23%)
MFS 123..510 CDD:119392 107/469 (23%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 537..557
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C166347160
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG57756
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
43.850

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