DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14691 and Slc22a20

DIOPT Version :9

Sequence 1:	NP_650012.2	Gene:	CG14691 / 41287	FlyBaseID:	FBgn0037829	Length:	522	Species:	Drosophila melanogaster
Sequence 2:	NP_001381833.1	Gene:	Slc22a20 / 293686	RGDID:	1311460	Length:	556	Species:	Rattus norvegicus

Alignment Length:	496	Identity:	98/496 - (19%)
Similarity:	185/496 - (37%)	Gaps:	152/496 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 CLTAMVFSASALSYVMPSA---ECDL--------DLSIVDKGMLHAVTYAGMIISAVPWGFIADT 91
            |....|:..|    :.||.   |.||        ||:       .::..:|:::.|..:|.:||.
  Rat   107 CKDGWVYDRS----IFPSTIVMEWDLVCEARTLRDLA-------QSIYMSGVLVGAALFGSLADR 160

  Fly    92 IGRRPVL--------ISG---GWLDGFFVLCASLSQNTAQLMAFKFFDGLIICGPFAVVVSYLAE 145
            :||:..|        :||   .::..|...|           .|:|..|:...|.....:|.:.|
  Rat   161 LGRKAPLVWSYLQLAVSGAVTAYVGSFSAYC-----------IFRFLMGMTFSGIILNSLSLVVE 214

  Fly   146 FHGKKHRPYIMLFVGLCVSIGSMILPLLSYLLLPVPILFTVSSMKFRTWQVFLAVSSAPSLLSGF 210
            :...:.|....:.:|...::|.:||..::||:.|              |:......|||.|:...
  Rat   215 WMPTRGRTVAGILLGFSFTLGQLILAGVAYLIRP--------------WRWLQFAVSAPFLVFFL 265

  Fly   211 LHIFLPESPKFLMSQGNYKKALDSLQRIYKLNKRKSR-ESYPIKHLTDPTPDRSDDLDGTGRPST 274
            ...:||||.::|:..|..::|:.:|:::..:|.||:. |...|:.::                |.
  Rat   266 YSWWLPESSRWLLLHGKAQQAVQNLRKVAMMNGRKAEGERLTIEVVS----------------SY 314

  Fly   275 LQERFS--RAQSKFIDGFKQ----------LKPMFSSPY----LAISLQVYCLHFCQIMCVNSVR 323
            :|..|:  |..:..:|.|:.          :...||:..    ||:.||.:.|....:..:..:
  Rat   315 IQNEFASVRTSNSILDLFRTPGIRKVTCCLMMVWFSNSVAYYGLAMDLQKFGLSIYLVQALFGI- 378

  Fly   324 LWLPQIFATMNAMDTLGANDTSMCAVLEHNANAKSMDEEEKRVECALHHDPDSYLNNITVAGIGL 388
            :.:|.:......|..:|...|                             ..|:|   .:||:.:
  Rat   379 IDIPAMLVATTTMIYVGRRAT-----------------------------VSSFL---VLAGLMV 411

  Fly   389 VGFLIIFP--LMRFQVVSNHILKVFL---FICIFL-VGSLYFVKTSLVTMMVSAVYLTMMGICA- 446
            :..:.: |  |...:.|...:.|..|   |||::| .|.||..:...:.|..::|...:.|:.|
  Rat   412 IANMFV-PEDLQTLRTVQAALGKGCLASSFICVYLFTGELYPTEIRQMGMGFASVNARLGGLAAP 475

  Fly   447 --------------------TTIIGMSVVIFPTLMRTMVLL 467
                                :.:.||:|:.|.|..|.:.|:
  Rat   476 LITTLGEISPVLPPVSFGATSVLAGMAVICFLTETRNVPLV 516

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14691	NP_650012.2	MFS	30..>216	CDD:119392	41/199 (21%)
Slc22a20	NP_001381833.1	MFS_SLC22A6_OAT1_like	103..508	CDD:341004	95/486 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166347021
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.850