Protein Alignment CG14691 and Slc22a19

DIOPT Version :10

• Sequence 1: NP_650012.2
• Gene: CG14691 / 41287
• FlyBaseID: FBgn0037829
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_775424.1
• Gene: Slc22a19 / 286961
• RGDID: 628885
• Length: 551
• Species: Rattus norvegicus
• Alignment Length: 556
• Identity: 105/556 - (18%)
• Similarity: 185/556 - (33%)
• Gaps: 194/556 - (34%)

  Fly    25 GLFNVFILCSAVPCLTAMVFSASALSYVMPSAECDLDLSIVDKGMLHAVT----YAGMIISAVPW 85
            |.|:........||:...|:..|..   :.:.....|| :.....|::|.    ..|:.|..:..
  Rat   103 GTFSTVTEPDTEPCVDGWVYDQSTF---LSTTVTQWDL-VCGSQTLNSVAKFIYMTGIFIGHLMG 163

  Fly    86 GFIADTIGRRPVLISGGWLDGFFVLCASLS---QNTAQLMAFKFFDGLIICG-PFAVVVS----- 141
            |.::|..||:           |.|.|..|:   ..|:...|..|   ||.|. .|...:|
  Rat   164 GHLSDKFGRK-----------FIVTCGLLTLAVTETSVAFAPTF---LIYCSLRFLTGISSSCIR 214

  Fly   142 -----YLAEFHGKKHRPYIMLFVGLCVSIGSMILPLLSYLLLPVPILFTVSSMKFRTWQVFLAVS 201
                 .:.|:...|.:..:|..:.....||.::|.:|::              ..|.||......
  Rat   215 TNSALLILEWTSPKFQAMVMALIFSAGGIGQVLLGVLAF--------------GIRNWQHLQLAM 265

  Fly   202 SAPSLLSGFLHI---FLPESPKFLMSQGNYKKALDSLQRIYKLNK-RKSRESYPIKHLTDPTPDR 262
            |.|..   ||.|   :|.||.::|:.....::.|..|.::..:|. :.||:...::.:
  Rat   266 SVPVF---FLLIPTRWLSESARWLIITNKPQEGLKELIKVAHINGIKNSRDVLTLEVV------- 320

  Fly   263 SDDLDGTGRPSTLQERFSRAQSKFIDGFKQLKPMFSSPYLAISLQVYCLHFCQIMCVNSVRLWLP 327
                     .:|:::....|::|            .||.:
  Rat   321 ---------KTTMKDELEAAETK------------PSPLV------------------------- 339

  Fly   328 QIFATMNAMDTLGANDTSMCAVLEHNANAKSMDEEEKRVECALHHDPDSYLNNITVAGIGLVGFL 392
             :|.|.|.                           .||: |.|     |::..:::  |..||.|
  Rat   340 -LFRTPNL---------------------------RKRI-CLL-----SFVRCVSL--ISTVGLL 368

  Fly   393 IIFPLMRFQVVSNHILKVFLFICIF--------LVGSLYFVKTSLVTMMVSAVYLTMMGICATTI 449
            |     ..|.:||   ||||..|::        |:|:  |....:.......:::::|||...:|
  Rat   369 I-----NLQYLSN---KVFLLQCLYGVVCTPANLLGN--FSMNYMGRRTTQIIFMSVMGISILSI 423

  Fly   450 ----------------IG-------------MSVVIFPTLMRTMVLLLIMTFGRLGSVSGNMLLP 485
                            :|             :|..:.||::|...|.:|..||..|:....:|:
  Rat   424 TFLTQEMQIPRLVLASLGGAISSASLTSTAVLSNELVPTVIRATALGVIGIFGSAGAALSPLLM- 487

  Fly   486 VFMQLSCLAPFLWLCSLMSIAFLFSLFLKVDDEQSL 521
            :.|..|...|::....|..::.|..|.|.....|.|
  Rat   488 ILMTYSASLPWIIYGVLPILSSLVVLLLPETRNQPL 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14691	NP_650012.2	synapt_SV2	2..>337	CDD:130366	60/333 (18%)
		MFS	<375..513	CDD:475125	38/174 (22%)
Slc22a19	NP_775424.1	MFS	109..506	CDD:475125	98/531 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	524..551		105/556 (19%)