DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14691 and SPAPB1E7.08c

DIOPT Version :9

Sequence 1:	NP_650012.2	Gene:	CG14691 / 41287	FlyBaseID:	FBgn0037829	Length:	522	Species:	Drosophila melanogaster
Sequence 2:	NP_594134.1	Gene:	SPAPB1E7.08c / 2543660	PomBaseID:	SPAPB1E7.08c	Length:	554	Species:	Schizosaccharomyces pombe

Alignment Length:	580	Identity:	121/580 - (20%)
Similarity:	209/580 - (36%)	Gaps:	148/580 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 RAKDNTDEPADF-----------ETAIAECGFGLFNVFILCSA----------VPCLTAMVFSAS 47
            ::.|:..:..||           ..|:.|.|||.:..::...|          ..|.:.::....
pombe    43 KSDDDLFDSNDFSKTYLAKSRILSNAMNEIGFGRYQWYLFFVAGFGWMSDNIWPVCTSLILMRLD 107

  Fly    48 ALSYVMPSAECDLDLSIVDKGMLHAVTYA---GMIISAVPWGFIADTIGRRPVLISGGW------ 103
            .:....|.||          |....:|.:   |:::.|:.|...|||||||       |
pombe   108 EVDGPHPPAE----------GRAPYLTLSQNLGLLVGAMVWSLSADTIGRR-------WAFNLTF 155

  Fly   104 -LDGFFVLCASLSQNTAQLMAFKFFDGLIICGPFAVVVSYLAEFHGKKHRPYIMLFVGLCVSIGS 167
             ..|.|.:.|..|.|.|.:..|.......:.|...|..:...|.....|: :::..:....:||.
pombe   156 LFTGVFAVIAGASPNFASICVFDALWSFGVGGNLPVDSAIFLEALPSSHQ-WLLTVMSFWWAIGQ 219

  Fly   168 MILPLLSYLLLPVPILFTVSSMKFRT----WQVFLAVSSAPSLL---SGFLHIFLPESPKFLMSQ 225
            :|..|:|:.|:.........|:..|.    |:.||......:||   :.|| :.:.|||||.:::
pombe   220 VIANLVSWGLISNFSCPDDESVCHRADNKGWRYFLFTMGGMTLLMFAARFL-VSVYESPKFYLAK 283

  Fly   226 GNYKKALDSLQRIYKLNKRKSRESYPIKHLTDPTPDRSDDLDGT----------GRPSTLQERFS 280
            |:..||::::.:|.::|.:....:....:..|.......|||.:          |..:.:.|:..
pombe   284 GDDYKAVETIHKIARINGKTCTLTVEELYAIDRQEQEESDLDDSKSSDAKSVTQGTTNLIVEKLR 348

  Fly   281 RAQSKFIDGFKQLKPMFSSPYLAISLQVYCLHFCQI-MCVNSVRLWLPQIFATM-NAMDTLGAND 343
            :.      .|:.::..|.|..||||..:..|.:..| :.......:||....|. ||.:.|....
pombe   349 KY------NFEHIRQCFGSRKLAISSILVILSWAVIGLAFPLYNAFLPYYLETRGNANEPLSVAK 407

  Fly   344 TSMCAVLEHNANAKSMDEEEKRVECALHHDPDSYLNNITVAGIGLVGFLIIFPLMRFQVVSNHIL 408
            |                                |.|::.|:.||:.|.||...|:.|::..
pombe   408 T--------------------------------YRNSLIVSAIGVPGSLIAGVLVEFRIGR---- 436

  Fly   409 KVFLFICIFLVGSLYFVKTSLVTMMVSAVYL-----------TMMGICATTIIGMSVVIFPTLMR 462
            |..|.:.:.|.|...|..|   |...|..||           .|.|:    :...:..:||:.:|
pombe   437 KGTLCLSLILTGVFLFAST---TAKTSNAYLGWNCTFSFFSDIMYGV----LYAYTPEVFPSKVR 494

  Fly   463 TMVLLLIMTFGRLGSVSGNMLLPVF-------MQLSCLAPFLWLCSLMSIAFLFSLFLKV 515
            ...:.|        :.|.|.:|.:|       ..|:..||..    :....|:|:..|.|
pombe   495 GTAVGL--------AASANRILGIFSPVIAMRANLTTSAPIF----VSGALFIFAGILVV 542

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14691	NP_650012.2	MFS	30..>216	CDD:119392	44/212 (21%)
SPAPB1E7.08c	NP_594134.1	2A0109	68..552	CDD:129965	118/555 (21%)
SPAPB1E7.08c	NP_594134.1	MFS	122..545	CDD:119392	107/491 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910