Protein Alignment CG14691 and Slc22a22

DIOPT Version :10

• Sequence 1: NP_650012.2
• Gene: CG14691 / 41287
• FlyBaseID: FBgn0037829
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: XP_036015188.1
• Gene: Slc22a22 / 210463
• MGIID: 2446114
• Length: 587
• Species: Mus musculus
• Alignment Length: 495
• Identity: 99/495 - (20%)
• Similarity: 177/495 - (35%)
• Gaps: 117/495 - (23%)

  Fly    37 PCLTAMVFSASALSYVMPSAECDLDLSIVDKGMLHAVTYAGMIISAVPWGFIADTIGRRPVLISG 101
            ||...:..|......|     ||....   |....|.:.||.::|....|.|:|..||:|:|:..
Mouse   155 PCEEGLKSSVKVWDLV-----CDFQSF---KYYAQATSLAGHLVSCPLSGIISDRFGRKPLLMYC 211

  Fly   102 GWLDGFFVLCASLSQNTAQLMAFKF----FDGLIICGPFAVVVSYLA-EFHGKKHRPYIMLFVGL 161
            ....|......:.:.|.:.....:|    |...|:.....:|:...: ::|     |.|::..||
Mouse   212 SLAYGAVGTYCAFAPNFSVYCVLRFLLSAFQSTILINSLILVLEEASVQWH-----PTIIVLSGL 271

  Fly   162 CVSIGSMILPLLSYLLLPVPILFTVSSMKFRTWQVFLAVSSAPSLLSGFLHIFLPESPKFLMSQG 226
            ..|||..:|..|:|::              ..|.:.....:.|..:...|..::|||.::|:..|
Mouse   272 FNSIGQGVLGGLAYVI--------------SDWHLLQLAYALPFFIFFVLFCWVPESVRWLIITG 322

  Fly   227 NYKKALDSLQRIYKLNKRKSRESYPIKHLT--DPTPDRSDDLDGTGRPSTLQERFSRAQSKFIDG 289
            ...:|...||||..:|.:|.    ..::||  |.......|::.||:...:::.|
Mouse   323 KTDQAWKELQRIASINGKKG----IAQNLTTEDLRSKLKKDVNSTGKLFRIKDIF---------- 373

  Fly   290 FKQLKPMFSSPYLAISLQVYCLHFCQIMCVNSVRL-----WLPQIFATMNAMDTLGANDTSMCAV 349
               :.|:.....|:.|..::...|..:..:..|:|     :|.|||        |||.|.
Mouse   374 ---INPLIRKIVLSNSSLLFAELFSFVGLLLDVQLLGKNMFLTQIF--------LGAIDV----- 422

  Fly   350 LEHNANAKSMDEEEKRVECALHHDPDSYLNNITVAGIG---LVGFLIIFPLMRFQVVSNHILKVF 411
                                    |...|...|:..:.   |:.||::            .....
Mouse   423 ------------------------PSKSLTYFTIRNVSRRPLIAFLLL------------TTGSC 451

  Fly   412 LFICIFLVGSLYFVKTSLVTMMVSAVYLTMMGICATTIIGMSVVIFPTLMRTMVLLLIMTFGRLG 476
            :.|.||:...:|.::| ::.::....:.....|..|.|..:|    |..:|:.:..:.:...||.
Mouse   452 ITITIFISEEMYVLRT-IIFILGKGCFAAFTCISTTYINELS----PVELRSTLNGVFLAVVRLA 511

  Fly   477 SVSGNMLLPVFMQLSCLAPFLW----LCSLMSIAFLFSLF 512
            .|...:.|........|...|:    :.:.:||.||...|
Mouse   512 GVLSALTLATRKYFVYLPMILYGVLPIVATISILFLPETF 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14691	NP_650012.2	synapt_SV2	2..>337	CDD:130366	67/311 (22%)
		MFS	<375..513	CDD:475125	27/145 (19%)
Slc22a22	XP_036015188.1	MFS_OAT	108..548	CDD:340932	97/490 (20%)