Protein Alignment CG14691 and Slc22a12

DIOPT Version :10

• Sequence 1: NP_650012.2
• Gene: CG14691 / 41287
• FlyBaseID: FBgn0037829
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_033229.3
• Gene: Slc22a12 / 20521
• MGIID: 1195269
• Length: 553
• Species: Mus musculus
• Alignment Length: 495
• Identity: 98/495 - (19%)
• Similarity: 166/495 - (33%)
• Gaps: 161/495 - (32%)

  Fly    37 PCLTAMVFSASAL-SYVMPSAE--CDLDLSIVDKGMLHAVTYAGMIISAVPWGFIADTIGRRPVL 98
            ||....|:..|.. |.::.:.:  |:   |...:.|..::..||:::.|...|..:|..|||.||
Mouse   115 PCEDGWVYDHSTFRSTIVTTWDLVCN---SQALRPMAQSIFLAGILVGAAVCGHASDRFGRRRVL 176

  Fly    99 ISGGWLDGFFVLCASLSQNTAQLM-------AFKFFDGLIICGPFAVVVSYLAEFHGKKHRPYIM 156
            .   |    ..|..|:|...|..|       .|:|.....:.|......|.|.|:...:..|.:|
Mouse   177 T---W----SYLLVSVSGTAAAFMPTFPLYCLFRFLLASAVAGVMMNTASLLMEWTSAQGSPLVM 234

  Fly   157 LFVGLCVSIGSMILPLLSYLLLPVPILFTVSSMKFRTWQVFLAVSSAPSLLSGFLHIFLPESPKF 221
            ....|..|.|.::...::|              ..|:|::.....|||..|......:||||.::
Mouse   235 TLNALGFSFGQVLTGSVAY--------------GVRSWRMLQLAVSAPFFLFFVYSWWLPESARW 285

  Fly   222 LMSQGNYKKALDSLQRIYKLNKRKSRESYPIKHLTDPTPDRSDDLDGTGRPSTLQERFSRAQSKF 286
            |::.|...:.|..|||:..:|:||:               ..|.|......|.::|..||.::.
Mouse   286 LITVGKLDQGLQELQRVAAVNRRKA---------------EGDTLTMEVLRSAMEEEPSRDKAG- 334

  Fly   287 IDGFKQLKPMFSSPYLAISLQVYCLHFCQIMCVNSVRLWLPQIFATMN-AMD--TLGANDTSMCA 348
                ..|..:..:|.|            :...:.|:..|....|.... |:|  .||:|...:.|
Mouse   335 ----ASLGTLLHTPGL------------RHRTIISMLCWFAFGFTFYGLALDLQALGSNIFLLQA 383

  Fly   349 VLEHNANAKSMDEEEKRVECALHHDPDSYLNNITVAGIGLVGFLIIFPLMRFQVVSNHILKVFLF 413
            :                                    ||:|.|.:
Mouse   384 L------------------------------------IGIVDFPV-------------------- 392

  Fly   414 ICIFLVGSLYFVKTSLVTMMVSAVYLTMMGIC----------------ATTIIGM---------- 452
                ..|||..: :.|...:....:|.:.|:|                |..::|:
Mouse   393 ----KTGSLLLI-SRLGRRLCQVSFLVLPGLCILSNILVPHGMGVLRSALAVLGLGCLGGAFTCI 452

  Fly   453 ---SVVIFPTLMRTMVLLLIMTFGRLGSVSGNM--LLPVF 487
               |..:|||::|...:.|.....|.|::.|.:  ||.|:
Mouse   453 TIFSSELFPTVIRMTAVGLCQVAARGGAMLGPLVRLLGVY 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14691	NP_650012.2	synapt_SV2	2..>337	CDD:130366	68/310 (22%)
		MFS	<375..513	CDD:475125	25/144 (17%)
Slc22a12	NP_033229.3	MFS_OAT	109..516	CDD:340932	98/495 (20%)