Protein Alignment CG14691 and Slc22a5

DIOPT Version :10

• Sequence 1: NP_650012.2
• Gene: CG14691 / 41287
• FlyBaseID: FBgn0037829
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_035526.1
• Gene: Slc22a5 / 20520
• MGIID: 1329012
• Length: 557
• Species: Mus musculus
• Alignment Length: 465
• Identity: 104/465 - (22%)
• Similarity: 191/465 - (41%)
• Gaps: 133/465 - (28%)

  Fly    75 YAGMIISAVPWGFIADTIGRRPVL-ISGGWLDGF-FVLCASLSQNTAQLMAFKFFDGLIICGPFA 137
            :.|:::.:...|.::|..||:.|| ::.|...|| |:...|::        |:.|..|.:.....
Mouse   150 FVGVLMGSFISGQLSDRFGRKNVLFLTMGMQTGFSFLQVFSVN--------FEMFTVLFVLVGMG 206

  Fly   138 VVVSYLA------EFHGKKHRPYIMLFVGLCV--SIGSMILPLLSYLLLPVPILFTVSSMKFRTW 194
            .:.:|:|      |...|..| .|...:|:|:  :.|.|:|||.:|.:              |.|
Mouse   207 QISNYVAAFVLGTEILSKSIR-IIFATLGVCIFYAFGFMVLPLFAYFI--------------RDW 256

  Fly   195 QVFLAVSSAPSLLSGFLHIFLPESPKFLMSQGNYKKALDSLQRIYKLNKRKSRESYPIKHLTDPT 259
            ::.|...:.|.:|.|.|..|:||||::|:|||..|:|...:::..|:|
Mouse   257 RMLLLALTVPGVLCGALWWFIPESPRWLISQGRIKEAEVIIRKAAKIN----------------- 304

  Fly   260 PDRSDDLDGTGRPSTLQERFSRAQSKFIDGFKQLKPMFSSPYLAISLQVYCLHFCQIMCVNSVRL 324
                    |...|||:   |..::   :......||.....|..|..:     ..:::.:.|:.|
Mouse   305 --------GIVAPSTI---FDPSE---LQDLNSTKPQLHHIYDLIRTR-----NIRVITIMSIIL 350

  Fly   325 WLPQIFATMNAMDTLGANDTSMCAVLEHNANAKSMDEEEKRVECALHHDPDSYLNNITVAGIGLV 389
            ||           |:......:           |:|...      ||  .|.|:|...:|.:.:.
Mouse   351 WL-----------TISVGYFGL-----------SLDTPN------LH--GDIYVNCFLLAAVEVP 385

  Fly   390 GFLIIFPLMRFQVVSNHILKVFLF----ICIF--LVGS-LYFVKTSLV-------TMMVSAVYLT 440
            .:::.:.|::: :...:.:...||    :.:|  ||.| |:::.|:||       |...|.||:
Mouse   386 AYVLAWLLLQY-LPRRYSISAALFLGGSVLLFMQLVPSELFYLSTALVMVGKFGITSAYSMVYV- 448

  Fly   441 MMGICATTIIGMSVVIFPTLMRTMVLLLIMTFGRLGSVSGNMLLPVFMQLSC---LAPFLWLCSL 502
                       .:..::||::|.|.:.:..|..||||:    |.|.|:.|..   ..|::.:.||
Mouse   449 -----------YTAELYPTVVRNMGVGVSSTASRLGSI----LSPYFVYLGAYDRFLPYILMGSL 498

  Fly   503 MSIAFLFSLF 512
            ..:..:.:||
Mouse   499 TILTAILTLF 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14691	NP_650012.2	synapt_SV2	2..>337	CDD:130366	62/271 (23%)
		MFS	<375..513	CDD:475125	37/155 (24%)
Slc22a5	NP_035526.1	2A0119	12..520	CDD:273328	104/465 (22%)