Protein Alignment CG14691 and oct-1

DIOPT Version :10

• Sequence 1: NP_650012.2
• Gene: CG14691 / 41287
• FlyBaseID: FBgn0037829
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_492617.4
• Gene: oct-1 / 172841
• WormBaseID: WBGene00003842
• Length: 585
• Species: Caenorhabditis elegans
• Alignment Length: 545
• Identity: 108/545 - (19%)
• Similarity: 191/545 - (35%)
• Gaps: 146/545 - (26%)

  Fly    12 PADFETAIAEC------GFGLFNVFILC---------SAVPCLTAMVFSASALSYVMPSAECDLD 61
            |...:|.|..|      ...:|..|...         |.|||.....:..|.   .:.|...:.:
 Worm    84 PLTNDTQILSCKQYNETQINVFRAFTSAPVDTYSDRISLVPCQNGWDYDNST---YLDSLVTEFN 145

  Fly    62 LSIVDKGMLHAVT---YAGMIISAVPWGFIADTIGRRPVLISGGWLDGFFVL------CASLSQN 117
            |....:..:...|   |.|..|....:|::||..|||         ..|||:      |.:.|..
 Worm   146 LVCDQQAWIEISTTSFYVGSFIGNCLFGYVADKFGRR---------RSFFVILTVLIVCGTASSF 201

  Fly   118 TAQLMAF---KFFDGLIICGPFAVVVSYLAEFHGKKHRPYIMLFVGLCVSI--GSMILPLLSYLL 177
            ...:.:|   :||.||.....|.:......||.|...|    :|.||..|:  |:.:
 Worm   202 AKDIESFIILRFFTGLAFPALFQIPFIICMEFMGNSGR----IFSGLMTSLFFGAAM-------- 254

  Fly   178 LPVPILFTVSSMKFRTWQVFLAVSSAPSLLSGFLHIFLPESPKFLMSQGNYKKALDSLQRIYKLN 242
                .|..|.:|..|.|:......:||.......:.||||||::.:|.|.:..|...|::|.|:|
 Worm   255 ----ALLGVVAMFIRRWRQLTFFCNAPFAFYIIYYFFLPESPRWSVSVGKWADAKKQLKKIAKMN 315

  Fly   243 KRKSRESYPIKHLTDPTPDRSDDLDGTGRPSTLQERFSRAQSKFIDGFKQLKPMFSSPYLAISLQ 307
               .:.:..:..|.|                :::...:.|:.|.......:..:|.:|.|.....
 Worm   316 ---GKSNVDVDELVD----------------SMKNHQNAAEEKETKRSHNVTDLFKTPNLRRKTL 361

  Fly   308 VYCLHFCQIMCVNSVRLWLPQIFATMNAMD----TLGANDTSMCAVLEHNANAKSMDEEEKRVEC 368
            :.            ..:|:      |||:.    ||..::..:
 Worm   362 IV------------TYIWV------MNAIIYNGLTLNVSNLPV---------------------- 386

  Fly   369 ALHHDPDSYLNNITVAGIGLVGFLIIFPLMRFQVVSNH-ILKVFLFICIFLVGSLYFVKTSLVTM 432
                  |.|.:.|....:.|.|:.:::||:  |..... .|...:.:|.....|..|:......:
 Worm   387 ------DDYWSFIINGAVELPGYFVVWPLL--QCAGRRWTLAATMIVCGIGCVSAMFMPDGYPWL 443

  Fly   433 MVSAVYLTMMGICATTIIGMSVV------IFPTLMRTMVLLLIMTFGRLGSVSGNMLLPVFMQLS 491
            :.||.::...|:.:    |.:|:      ::||::|.    :.|....:.:.||.:|.|..:.|.
 Worm   444 VASASFIGKFGVGS----GFAVIYIFAGELYPTVVRA----IGMGMSSMVAGSGLLLAPHIVNLG 500

  Fly   492 CLAPF--LWLCSLMSI-AFLFSLFL 513
            .:...  |.:..||:: |.:.:.||
 Worm   501 KIVKILPLLIMGLMALSAGILTFFL 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14691	NP_650012.2	synapt_SV2	2..>337	CDD:130366	74/353 (21%)
		MFS	<375..513	CDD:475125	30/147 (20%)
oct-1	NP_492617.4	MFS_SLC22	128..526	CDD:340875	98/501 (20%)