DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14691 and Svop

DIOPT Version :9

Sequence 1:	NP_650012.2	Gene:	CG14691 / 41287	FlyBaseID:	FBgn0037829	Length:	522	Species:	Drosophila melanogaster
Sequence 2:	NP_599231.3	Gene:	Svop / 171442	RGDID:	620277	Length:	548	Species:	Rattus norvegicus

Alignment Length:	537	Identity:	123/537 - (22%)
Similarity:	218/537 - (40%)	Gaps:	118/537 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 TDEPADFETAIAECGFGLFNVFILCSAVPCLTAMVFSASA-----LSYVMPSAECDLDLSIVDKG 68
            ||:....|.|:...|||.|.     ..:..||.:.:.|.|     ||.:.|...|:..|......
  Rat    64 TDDTFMVEDAVEAIGFGRFQ-----WKLSVLTGLAWMADAMEMMILSILAPQLHCEWRLPSWQVA 123

  Fly    69 MLHAVTYAGMIISAVPWGFIADTIGRRPVL-ISGGWLDGFFVLCASLSQNTAQLMAFKFFDGLII 132
            :|.:|.:.||:.|:..||.|:|..||:..| ||..|...:.:|.| .:...:.::..:...|..|
  Rat   124 LLTSVVFIGMMSSSTLWGNISDQYGRKTGLKISVFWTLYYGILSA-FAPVYSWILVLRGLVGFGI 187

  Fly   133 CGPFAVVVSYLAEFHGKKHRPYIMLFVGLCVSIGSMILPLLSYLLLPVPILFTVSSMKFRTWQVF 197
            .|....|..| |||...|.|...:|.:.:..:||::...||:..::|        |:   .|:..
  Rat   188 GGVPQSVTLY-AEFLPMKARAKCILLIEVFWAIGTVFEVLLAVFVMP--------SL---GWRWL 240

  Fly   198 LAVSSAPSLLSGFLHIFLPESPKFLMSQGNYKKALDSLQRIYKLNKRKSRESYPIKHLTDPTPDR 262
            |.:|:||.|:...|..:||||.::.:..||.:||:.:|:||...|
  Rat   241 LLLSAAPLLVFAVLCFWLPESARYDVLSGNQEKAIATLKRIATEN-------------------- 285

  Fly   263 SDDLDGTGRPSTLQER-FSRAQSKFIDGFKQLKPMFSSPYLAISLQVYCLHFCQIMCVNSVRLWL 326
                   |.|..|.:. .||.:.:     .:::.:|:..:...:|.::.:.|........:.|..
  Rat   286 -------GAPMPLGKLIISRQEDR-----GKMRDLFTPHFRWTTLLLWFIWFSNAFSYYGLVLLT 338

  Fly   327 PQIFATMNAMDTLGANDTSMCAVLEHNANAKSMDEEEKRVE--CAL---HHDPDSYLNNITVA-- 384
            .::|.         |.|  :|          |:...:|.||  |:|   :...:.|::.:...
  Rat   339 TELFQ---------AGD--VC----------SISSRKKAVEAKCSLACEYLSKEDYMDLLWTTLS 382

  Fly   385 ---GIGLVGFLIIFPLMR-------FQVVSNHILKVFLFICI--FLVGSLYFVKTSLVTMMVSAV 437
               |: ||...:|..|.|       |.:.|  :..:.|||||  .::..|.|:..:.::....|.
  Rat   383 EFPGV-LVTLWVIDRLGRKKTMALCFVIFS--LCSLLLFICIGRNVLTLLLFIARAFISGGFQAA 444

  Fly   438 YLTMMGICATTIIGMSVVIFPTLMRTMVLLLIMTFGRLGSVSGNMLLPVFMQLS---CLAPFLWL 499
            |:            .:..::||..|.:.|.......|:|::....:..|.::.|   .||.:...
  Rat   445 YV------------YTPEVYPTATRALGLGTCSGMARVGALITPFIAQVMLESSVYLTLAVYSGC 497

  Fly   500 CSLMSIAFLFSLFLKVD 516
            |.|.::|   |.||.::
  Rat   498 CLLAALA---SCFLPIE 511

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14691	NP_650012.2	MFS	30..>216	CDD:119392	50/191 (26%)
Svop	NP_599231.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	523..548
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010