Protein Alignment CG14691 and sv2b

DIOPT Version :9

• Sequence 1: NP_650012.2
• Gene: CG14691 / 41287
• FlyBaseID: FBgn0037829
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: XP_002933355.1
• Gene: sv2b / 100497731
• XenbaseID: XB-GENE-6041859
• Length: 711
• Species: Xenopus tropicalis
• Alignment Length: 612
• Identity: 128/612 - (20%)
• Similarity: 244/612 - (39%)
• Gaps: 117/612 - (19%)

  Fly     1 MADRAKDNTDEPADFETAIAECGFGLF--NVFILCSAVPCLTAMVFSASALSYVMPSAECDLDLS 63
            :|:|.:|.......:|..|.|||.|.|  .:|::...  .|.|.......:.:|:||||.|:.||
 Frog   109 IAERIEDEEQLAYQYENIIQECGHGRFQWTLFVVLGL--ALMADGVEVFVVGFVLPSAEKDMCLS 171

  Fly    64 IVDKGMLHAVTYAGMIISAVPWGFIADTIGRRPVLISGGWLDGFFVLCASLSQNTAQLMAFKFFD 128
            ..:||||..:.|.||::.|..||.:||.:||:..||....::..|...:|..|.....:..:...
 Frog   172 RSNKGMLGLIVYLGMMLGAFVWGGLADKVGRKKCLIISLTINAAFSFVSSFVQGYGLFLFCRLIS 236

  Fly   129 GLIICGPFAVVVSYLAEFHGKKHRPYIMLFVGLCVSIGSMILPLLSYLLLP-VPILFTVSS-MKF 191
            |..|.|...:|.:|.:||..::.|...:.::.:...||::....:::.::| ....|::.: ..|
 Frog   237 GFGIGGSLPIVFAYFSEFLAREKRGEHLSWLCMFWMIGAVYAAAMAWSIIPHYGWGFSMGTHYHF 301

  Fly   192 RTWQVFLAVSSAPSLLSGFLHIFLPESPKFLMSQGNYKKALDSLQRIYKLNKRKSRES---YPIK 253
            .:|:||:.:...|.:.|.....|:||||:||:..|.:.:|...|:.|:..|.|...|.   :.:.
 Frog   302 HSWRVFVVICVLPCIASIIALKFMPESPRFLLETGKHDEAWMILKNIHDTNMRAKGEPEKVFTVS 366

  Fly   254 HLTDP-TPDRSDDL-DGTGRPSTLQERFSRAQSKFIDGFKQLKPMFSSPYLAISLQVYCLHFCQI 316
            |:..| .||...:: ..||  :..|..|.|..:.....::.:...||..:...::.:..:.|...
 Frog   367 HIKTPKQPDEFIEIQSSTG--TWFQRWFVRIMTVIKQIWENMLHCFSGQFRKNTIFLAVVWFTMS 429

  Fly   317 MCVNSVRLWLPQIFATMNAMDTLGANDTSMCAVLEHNANAKSMDEEEKR-------VECALHHD- 373
            :....:.:|.|.....:...|              :.:..|...:|..:       :|..:|.|
 Frog   430 LSYYGLTVWFPDTIRYLQDED--------------YASKVKRFTDENVKNFNFNFTLENQIHEDG 480

  Fly   374 ----------------------PDSYLNNITVAGIGLVGFLI---IF---PLMRFQVVSNHILKV 410
                                  .:.|..::|..|.......|   :|   .|.:.:.:..:.:.|
 Frog   481 EYYNDRFYKMKLKYVTFKDSLFDECYFEDVTSTGSIFENCTIQNTVFYNTDLYQHKFIDCNFINV 545

  Fly   411 ------------------FLFICIFLVGSLYFVKTSLV----------------TMMVSAV---Y 438
                              ||...:..:|||..:..:::                :|::|||   :
 Frog   546 TFSQPKEGCHIDFEEDNDFLIYLVSFLGSLSVLPGNIISALLMDKIGRIRMIAGSMLISAVCCFF 610

  Fly   439 L-------TMMG----ICATTIIG------MSVVIFPTLMRTMVLLLIMTFGRLGSVSGNMLLPV 486
            |       .|:|    .|.|:|..      ::|.::||..|.....::....:|.::.||.:...
 Frog   611 LFFGNSESAMIGWQCLFCGTSIAAWNALDVVTVELYPTNKRATAFGILNGLCKLAAIFGNSIFAS 675

  Fly   487 FMQLSCLAPFLWLCSLMSIAFLFSLFL 513
            |:.::.:.|.|...:.:....|.||.|
 Frog   676 FVGITKVIPILLASTALVGGGLISLRL 702

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14691	NP_650012.2	MFS	30..>216	CDD:119392	49/187 (26%)
sv2b	XP_002933355.1	synapt_SV2	1..711	CDD:130366	128/612 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D724235at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920