Protein Alignment CG14691 and slc22a5

DIOPT Version :10

• Sequence 1: NP_650012.2
• Gene: CG14691 / 41287
• FlyBaseID: FBgn0037829
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: XP_002934410.2
• Gene: slc22a5 / 100486941
• XenbaseID: XB-GENE-484416
• Length: 550
• Species: Xenopus tropicalis
• Alignment Length: 505
• Identity: 119/505 - (23%)
• Similarity: 198/505 - (39%)
• Gaps: 135/505 - (26%)

  Fly    37 PCLTAMVFSASA-LSYVMP--SAECDLDLSIVDKGML-HAVTYAGMIISAVPWGFIADTIGRRPV 97
            |||....:|.|. ||.::.  :..|:.|.    ||.| .::.:.|::|.:...|.::|..||:.|
 Frog   108 PCLDGWNYSKSLYLSTIVTEWNLVCENDW----KGPLTTSLFFVGVLIGSFVSGQMSDRFGRKKV 168

  Fly    98 LISGGWLDGFFVLCASLSQNTAQLMAFKFFDGLIICGPFAVVVSYL------AEFHGKKHRPYIM 156
            |.:...:...|.:....|.|      ::.|..|.|......:.:|:      ||...|..| .|.
 Frog   169 LFATMAVQTGFSIIQVFSVN------WEMFTALFIIVGMGQISNYVAAFILGAEILDKSVR-IIF 226

  Fly   157 LFVGLCV--SIGSMILPLLSYLLLPVPILFTVSSMKFRTWQVFLAVSSAPSLLSGFLHIFLPESP 219
            ..:|:|:  :||.|:|||.:|.:              |.|:..|...:.|.|....|...:||||
 Frog   227 STLGVCIFYAIGYMLLPLFAYFI--------------RDWRTLLLALTIPGLFCIPLWWIIPESP 277

  Fly   220 KFLMSQGNYKKALDSLQRIYKLNKRKSRESYPIKHLTDPTPDRSDDLDGTGRPSTLQER--FSRA 282
            ::|:|||.:::|.|.:::..|.|           .:|.|        |.....:.|||:  .:..
 Frog   278 RWLISQGRFQEAEDIIRKAAKKN-----------GITPP--------DSIFNFTELQEQKELTHK 323

  Fly   283 QSKFIDGFKQLKPMFSSPYLAISLQVYCLHFCQIMCVNSVRLWLPQIFATMNAMDTLGANDTSMC 347
            ...|:|..|...                   .:|:...|:.||:         :.::|....|:
 Frog   324 SHTFLDLLKTRN-------------------IRIITFLSILLWM---------IISVGYFGLSL- 359

  Fly   348 AVLEHNANAKSMDEEEKRVECALHHDPDSYLNNITVAGIGLVGFLIIFPLM-----RFQVVSNHI 407
                   |..:           ||.||  |:|....|.|.:..::|.:.|:     |:...|..:
 Frog   360 -------NTPN-----------LHGDP--YVNCFLSAIIEVPAYVIAWLLLRSFPRRYSTASTLV 404

  Fly   408 L--KVFLFICIFLVGSLYFVKTSLVTMMVSAVYLTMMGICATTIIGMSVV----IFPTLMRTMVL 466
            |  .|.|||        ..|...|..:.:..|.|...||  |:...|..|    ::||::|.|.:
 Frog   405 LGGVVLLFI--------QLVPQELGILSIVLVMLGKFGI--TSAFSMVYVYTAELYPTVVRNMGV 459

  Fly   467 LLIMTFGRLGSVSGNMLLPVFMQLSC---LAPFLWLCSLMSIAFLFSLFL 513
            .......|:||:    |.|.|:.|..   ..||:.:.||..:..:|:|.|
 Frog   460 GASSMASRMGSI----LSPYFVYLGAYDRFLPFILMGSLTVLIGMFTLCL 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14691	NP_650012.2	synapt_SV2	2..>337	CDD:130366	72/313 (23%)
		MFS	<375..513	CDD:475125	39/151 (26%)
slc22a5	XP_002934410.2	2A0119	12..516	CDD:273328	119/505 (24%)