Protein Alignment CG14691 and sv2ba

DIOPT Version :10

• Sequence 1: NP_650012.2
• Gene: CG14691 / 41287
• FlyBaseID: FBgn0037829
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_001076464.1
• Gene: sv2ba / 100009626
• ZFINID: ZDB-GENE-070209-134
• Length: 689
• Species: Danio rerio
• Alignment Length: 614
• Identity: 135/614 - (21%)
• Similarity: 241/614 - (39%)
• Gaps: 154/614 - (25%)

  Fly     1 MADRAKDNTDEPADFETAIAECGFG--------LFNVFILCSAVPCLTAMVFSASALSYVMPSAE 57
            ||...::.| .|..:|:.:.:||.|        |..:.::...|.|.        .:|:.:||||
Zfish    86 MAAEVEEET-LPDQYESIMEDCGHGRFQWTLFTLLGLALMADGVECF--------VVSFALPSAE 141

  Fly    58 CDLDLSIVDKGMLHAVTYAGMIISAVPWGFIADTIGRRPVLISGGWLDGFFVLCASLSQNTAQLM 122
            .|:.||..|||||..:.|.||:|.||.||.:||.:||:..|:....::..|...:..:|.....:
Zfish   142 KDMCLSNADKGMLGLIVYVGMMIGAVVWGGLADKLGRKQCLLYALAINCIFSFLSCFAQGYGFFI 206

  Fly   123 AFKFFDGLIICGPFAVVVSYLAEF-----HGKKHRPYIMLFVGLCVSIGSMILPLLSYLLLP-VP 181
            .|:...|:.|.|...||.:|.|||     .| :|..::.||    ..:|.:.....::.::| ..
Zfish   207 FFRLCSGIGIGGSIPVVYTYYAEFLQMDKRG-EHLSWLCLF----WMLGGLYASFTAWGIIPHYG 266

  Fly   182 ILFTV-SSMKFRTWQVFLAVSSAPSL--LSGFLHIFLPESPKFLMSQGNYKKALDSLQRIYKLN- 242
            ..|:: :..:|.:|:||:.|...||:  |:|.  :|:||||:||:....:.:|...|:|::..|
Zfish   267 WGFSMGTEFQFHSWRVFVLVCFLPSVAALAGL--VFMPESPRFLLESARHDEAWMILRRVHDTNW 329

  Fly   243 --KRKSRESYPIKHLTDPTPDRSDD--LDGTGRPSTLQERFSRAQSKFIDGFKQ-LKPMFS--SP 300
              |.:....:.:..:  .||...||  ::......|..:||...|...:   || :|.|.|  :|
Zfish   330 GAKGEPERVFQVSQI--KTPQTQDDEFIEIQSETGTAFQRFMVRQMTLV---KQVMKNMLSLAAP 389

  Fly   301 YLAI-SLQVYCLHFCQIMCVNSVRLWLP-QI--------------------------FATMNAM- 336
            .:.: .|.:..:.|........:..|.| ||                          |...|.:
Zfish   390 DVRLHGLFIAIVWFTMAFSYYGLGTWFPDQIKYLQFEEYESNVKIFHRERVERFHFNFTLQNQLH 454

  Fly   337 ---------------------DTLGAN----DTSMCAVLEHNANAKS-------MDEEEKRVECA 369
                                 |:|..|    |.........|...|:       :.|:.|.:.|.
Zfish   455 KEGEYVHDRFINIEIRNVKFEDSLFENCYFEDIKSTETFFENCTLKNTVFYNTDLWEDSKFINCN 519

  Fly   370 LHHDP----------------------DSYLNNITVAGIGLVGFLIIFPLMRFQVVSNHIL---- 408
            |.:..                      ||:|.:::|....::..|::..:.|.:::...:|
Zfish   520 LENTTFLHPKKGCHLNFQEENDILIYLDSFLGSLSVIPGNILAGLLMDKIGRLKIIGGSMLGSAV 584

  Fly   409 ------------KVFLFICIFL-VGSLYFVKTSLVTMMV------SAVYLTMMGICATTIIGMSV 454
                        .|.||.|:|. .|:..:....:||:.:      :..:..:.|.|....|..|.
Zfish   585 CTFFLLLCFSQWAVVLFQCLFFAAGAAAWNGIEVVTVELYPASKRATAFGVLNGTCKLAAIISSF 649

  Fly   455 VIFPTLMRTMVLLLIMTFGRLGSVSGNML 483
            :....:..|.::.:|::|..|  |.|.:|
Zfish   650 IFGKFIGITKIIPIILSFSAL--VCGGLL 676

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14691	NP_650012.2	synapt_SV2	2..>337	CDD:130366	98/409 (24%)
		MFS	<375..513	CDD:475125	26/132 (20%)
sv2ba	NP_001076464.1	synapt_SV2	36..689	CDD:130366	135/614 (22%)