DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14691 and si:dkey-166k12.1

DIOPT Version :9

Sequence 1:	NP_650012.2	Gene:	CG14691 / 41287	FlyBaseID:	FBgn0037829	Length:	522	Species:	Drosophila melanogaster
Sequence 2:	XP_001341287.1	Gene:	si:dkey-166k12.1 / 100001249	ZFINID:	ZDB-GENE-120215-78	Length:	537	Species:	Danio rerio

Alignment Length:	521	Identity:	110/521 - (21%)
Similarity:	180/521 - (34%)	Gaps:	158/521 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 CLTAMVFSASALSYVMPSAECDLDLSIVDKGML----HAVTYAGMIISAVPWGFIADTIGRRPVL 98
            |.|..|:|.........: |.||   :.||..|    .::...|:::.||.:|.:||..|||..:
Zfish    96 CETGWVYSHEVFQSTTVT-EWDL---VCDKRGLSSLGSSIYMLGLLVGAVVFGAMADRYGRRFAM 156

  Fly    99 ISGGWLDGFFVLCASLSQNTAQLMAFKFFDGLIICGPFAVVVSYL--AEFHGKKHRPYIMLFVGL 161
            :....|...|.:.|:.:.|....:..:|..|:.:.|  .::.:::  .|:...:.|....:|...
Zfish   157 LVSLALQTVFGVAAAFAPNFPVYVGLRFIIGMTVSG--VIINAFVLGTEWTCTQRRMLAGIFTDY 219

  Fly   162 CVSIGSMILPLLSYLLLPVPILFTVSSMKFRTWQVFLAVSSAPSLLSGFLHIF----LPESPKFL 222
            ....|.|:|..:::|:              |.|:......|||    |||.||    ||.|.::|
Zfish   220 FFGFGYMLLAGVAFLI--------------RDWRKLQLAISAP----GFLFIFYIWVLPHSARWL 266

  Fly   223 MSQGNYKKALDSLQRIYKLNKRKSRESYPIKHLTDPTPDRSDDLDGTGRPSTLQ-ERFSRAQSKF 286
            :.....::|:|.|::...:|                         |...|.|:| ||:...|.:
Zfish   267 LVNNRKEEAIDLLRKAASVN-------------------------GRTLPPTVQVERYESPQGR- 305

  Fly   287 IDGFKQLKPMFSSPYLAISL--------QVYCLHFCQIMCVNSVRLWLPQIFATMNAMDTLGAND 343
                        |.|..:.|        :...|.:          :|...:......  :||.:|
Zfish   306 ------------SKYTVVDLLRTPQMRKRALILFY----------IWFVNVLVYYGL--SLGVSD 346

  Fly   344 TSMCAVLEHNANAKSMDEEEKRVECALHHDPDSYLNNITVAGIGLVGF------LIIFPLMRFQV 402
            ..                            .|.||....   .|||..      |::.|..|
Zfish   347 LG----------------------------ADLYLTQFM---FGLVEIPARTLVLVLLPCSR--- 377

  Fly   403 VSNHILKVFLFI----CIF---LVGSLYFVKTSLVTMMVSAVYLTMMGICAT--TIIGMSVVIFP 458
              ...|.|||.:    |:.   |......|:|:|.  ||.     ..||.|:  .|...|..:||
Zfish   378 --KIPLSVFLVVGGGACLLTLTLPADSAHVRTALA--MVG-----KFGITASFAIIYVYSAELFP 433

  Fly   459 TLMRTMVLLLIMTFGRLGSVSGNMLLPVFMQL---SCLAPFLWLCSLMSIAFLFSLFLKVDDEQS 520
            |::|...:.:...|.|:|.|    |.|:...|   :.:.|.|...|...:|...:|.|.....|.
Zfish   434 TVLRQTGIGVSSMFARMGGV----LAPLINLLGRHTPVVPMLIFGSTPLLAAALALALPETARQP 494

  Fly   521 L 521
            |
Zfish   495 L 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14691	NP_650012.2	MFS	30..>216	CDD:119392	43/187 (23%)
si:dkey-166k12.1	XP_001341287.1	2A0119	11..497	CDD:273328	110/521 (21%)
si:dkey-166k12.1	XP_001341287.1	MFS	123..458	CDD:119392	92/451 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170588761
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.850