DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14691 and slc22a5

DIOPT Version :9

Sequence 1:	NP_650012.2	Gene:	CG14691 / 41287	FlyBaseID:	FBgn0037829	Length:	522	Species:	Drosophila melanogaster
Sequence 2:	XP_021324939.1	Gene:	slc22a5 / 100000685	ZFINID:	ZDB-GENE-091012-1	Length:	549	Species:	Danio rerio

Alignment Length:	504	Identity:	103/504 - (20%)
Similarity:	190/504 - (37%)	Gaps:	136/504 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 CLTAMVFSASALSYVMPS---AECDLDLSIVDKGMLHAVTYAGMIISAVPWGFIADTIGRRPVLI 99
            |....|:||......:.|   ..||.:..:   .:..:..|.|.::.::..|.::|..||:.||.
Zfish   111 CEDGWVYSADVYHSTIVSEWDLVCDSEWRV---PLASSTLYMGYLLGSIVSGQLSDRFGRKKVLF 172

  Fly   100 SGGWLDGFFVLCASLSQNTAQLMAFKFFDGLIICGPFAVVVSYLAEFHGKKHRPYIMLFV----- 159
                        .||:.....:.|..|....:|   |.|:..::..|   :...||..||
Zfish   173 ------------GSLAAEALLMFAQSFSPSWLI---FCVLYFFIGAF---QISLYITAFVLGNEV 219

  Fly   160 ------GLCVSIGSMILPLLSYLLLPVPILFTVSSMKFRTWQVFLAVSSAPSLLSGFLHIFLPES 218
                  .|..::|:.:...:.|:|||. :.|.:     |.|:..|.|.|..:::...|...:|||
Zfish   220 LSGSLRVLFTTLGAFLHYCVGYMLLPW-VAFAI-----RHWRTLLRVLSGLTVVYIPLWWLIPES 278

  Fly   219 PKFLMSQGNYKKALDSLQRIYKLNKRKSRESYPIKHLTDPTPDRSDDLDGTGRPSTLQERFSRAQ 283
            |::|:|||:.:::    :.|.:...||:|.         |.|               :..|.::|
Zfish   279 PRWLLSQGHVQES----EAILRDAARKNRV---------PAP---------------EVIFKQSQ 315

  Fly   284 SKFIDGFKQLKPMF-SSPYLAIS-LQVYCLHFCQIMCVNSVRLWLPQIFATMNAMDTLGANDTSM 346
            .|        :..| .|.|.|:. |:...:.....||   :.||:    |.......|..|.|:
Zfish   316 IK--------EAAFQKSKYSALDVLRTSNIRRTTFMC---LLLWM----AINIGYFGLSLNTTN- 364

  Fly   347 CAVLEHNANAKSMDEEEKRVECALHHDP--DSYLNNITVAGIGLVGFLIIFPLMRFQVVSNHILK 409
                                   |..||  :.:|:.:|.....:|...::....|     ..:|.
Zfish   365 -----------------------LSGDPFLNCFLSAVTEVPAYIVSTFLLKSCPR-----RPVLS 401

  Fly   410 VFLFICIFLVGSLYFVKTSLV--TMMVSAVYLTMMG-----ICATTIIGMSVVIFPTLMRTMVLL 467
            .||     ::|..:.:...|:  .:...|:.|.|.|     :..|.:...:..::||::|.:.:.
Zfish   402 AFL-----VIGGGFLLLVQLIPDRLQTLALALEMAGKFGFTMSFTVVYIYTAELYPTVLRNLGMG 461

  Fly   468 LIMTFGRLGSVSGNMLLPVFMQLSCL---APFLWLCSLMSIAFLFSLFL 513
            :..:..|:||::.    |..:.|...   .|::.:.||...|.|.:|||
Zfish   462 MCSSAARIGSITA----PYIIFLGTFNRHLPYVLMGSLTITASLANLFL 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14691	NP_650012.2	MFS	30..>216	CDD:119392	40/191 (21%)
slc22a5	XP_021324939.1	Sugar_tr	12..516	CDD:331684	103/504 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170588423
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.940