Protein Alignment TkR86C and HCAR3

DIOPT Version :9

• Sequence 1: NP_001097741.1
• Gene: TkR86C / 41286
• FlyBaseID: FBgn0004841
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_006009.2
• Gene: HCAR3 / 8843
• HGNCID: 16824
• Length: 387
• Species: Homo sapiens
• Alignment Length: 383
• Identity: 93/383 - (24%)
• Similarity: 169/383 - (44%)
• Gaps: 73/383 - (19%)

  Fly    62 DFLTECLFPSPTRPYELPWEQKTIWAIIFGLMMFVAIAGNGIVLWIVTGHRSMRTVTNYFLLNLS 126
            ||:.:.|.|                  :.||.....:.|||:.|||...|......:..||.||:
Human    24 DFIAKVLPP------------------VLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLA 70

  Fly   127 IAD-LLMSSLNCVFNFIFMLNSDWPFGSIYCTINNFVANVTVSTSVFTLVAISFDRYIAIVHP-- 188
            :|| ||:..|..|.:: ::..|||.||.|.|.:..|:..:....|:..|..::.|||..:|||
Human    71 VADFLLIICLPFVMDY-YVRRSDWKFGDIPCRLVLFMFAMNRQGSIIFLTVVAVDRYFRVVHPHH 134

  Fly   189 LKRRTSRRKVRIILVLIWALSCVLSAPCLLYSSIMTKHYYNGKSRTVC--FMMWPDGRYPTSMAD 251
            ...:.|.....||..|:|.::..|:.. ||...::.:   || :..||  |.:....|:..:|
Human   135 ALNKISNWTAAIISCLLWGITVGLTVH-LLKKKLLIQ---NG-TANVCISFSICHTFRWHEAM-- 192

  Fly   252 YAYNLIILVLTYGIPMIVMLICYSLMGRVLWGSRSIGENTDRQMESMKSKRKVVRMFIAIVSIFA 316
                   .:|.:.:|:.::|.|   ..|::|..|      .|||:.....::.:...:.:..:|.
Human   193 -------FLLEFFLPLGIILFC---SARIIWSLR------QRQMDRHAKIKRAITFIMVVAIVFV 241

  Fly   317 ICWLP-----YHLFFIYAYHNNQVASTKYVQHMYLGFYWLAMS----NAMVNPLIYYWMNKRFRM 372
            ||:||     .|:|::  .|.:...:.:..:.:.|.|: :.:|    |:|::|::||:.:..|..
Human   242 ICFLPSVVVRIHIFWL--LHTSGTQNCEVYRSVDLAFF-ITLSFTYMNSMLDPVVYYFSSPSFPN 303

  Fly   373 YFQRIICCCCVGLTRHRFDSPKSRLTNKNSSNRHTRGGYTVAHSLPNSSPPTTQTLLA 430
            :|..:|..|.           :.::|.:..:||.|....|   ..||.:....:.|:|
Human   304 FFSTLINRCL-----------QRKITGEPDNNRSTSVELT---GDPNKTRGAPEALIA 347

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR86C	NP_001097741.1	7tm_4	92..376	CDD:304433	77/297 (26%)
		7tm_1	100..363	CDD:278431	72/276 (26%)
HCAR3	NP_006009.2	7tm_1	44..294	CDD:278431	72/276 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	319..343		6/26 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910