Protein Alignment TkR86C and prlh2r

DIOPT Version :10

• Sequence 1: NP_001097741.1
• Gene: TkR86C / 41286
• FlyBaseID: FBgn0004841
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_001108619.1
• Gene: prlh2r / 797157
• ZFINID: ZDB-GENE-120411-41
• Length: 371
• Species: Danio rerio
• Alignment Length: 371
• Identity: 92/371 - (24%)
• Similarity: 169/371 - (45%)
• Gaps: 38/371 - (10%)

  Fly    52 DNLESINEAKDFLTECLFPSPTRPYELPWEQKTIWAIIFGLMMFVAIAGNGIVLWIVTGHRSMRT 116
            |:|.  ||::..::..|..|.....:|..:.|.::..::.:::.:|.:||.::|.::..::.:.:
Zfish     5 DDLH--NESRRNISLDLSSSSFTGLQLLMDLKPLFIPLYTMLVLIACSGNLLLLILIGLNKKLHS 67

  Fly   117 VTNYFLLNLSIADLLMSSLNCVF-----NFIFMLNSDWPFGSIYCTINNFVANVTVSTSVFTLVA 176
            .||:.:.||::.||:|    |:|     .|.......|.||...|.....:...||..:|.:|.|
Zfish    68 TTNFLIGNLALVDLVM----CLFCVPLTAFYAFDERGWVFGQFMCHFVTLMQTATVFAAVLSLTA 128

  Fly   177 ISFDRYIAIVHPLKRRTSRRKVRIILVLIWALSCVLSAPCLLYSSIMTKHYYNGKSRTVCFMMWP 241
            |:.|||:.:.:|::||..|.....::|.||..:..:|.|..|: ::.......|....||...|
Zfish   129 IAVDRYVVVAYPIRRRGGRWFCGWLVVSIWLCALAMSTPTALH-TVYLDLSETGHEMAVCEEFW- 191

  Fly   242 DGRYPTSMADYAYNLIILVLTYGIPMIVMLICY-----SLMGRVLWGSRSIGENTDRQMESMKSK 301
               :...::...|:...|:|:|.:|:..:.|.|     .|..|..  .|.:......|.:..:.:
Zfish   192 ---HGQELSRLIYSCFFLLLSYFVPLAAVSISYCAISCHLQHRAT--PRLMAATPSNQEKWGRKR 251

  Fly   302 RKVVRMFIAIVSIFAICWLPYHLFFIYAYHNNQVA--STKYVQHMYLGFYWLAMSNAMVNPLIYY 364
            ||..|:.:..|..||..|||..:..:....:...|  |..:|..:.:..:.||||:|..||.||.
Zfish   252 RKTFRLLLVSVLSFAFSWLPLQIVNLIRDLDTDFAILSKNHVNVIQVSCHLLAMSSACYNPFIYA 316

  Fly   365 WMNKRFRMYFQRIICCCCVGLTRHRFDSPKSRLTNKN--SSNRHTR 408
            .::|:|..|           |..:.|...|:..|..:  :|:|.||
Zfish   317 SLHKKFLSY-----------LCHNMFQKRKAHCTQSSITTSSRMTR 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR86C	NP_001097741.1	7tmA_TACR	84..374	CDD:320512	75/301 (25%)
		TM helix 1	85..111	CDD:320512	4/25 (16%)
		TM helix 2	118..144	CDD:320512	10/30 (33%)
		TM helix 3	156..186	CDD:320512	10/29 (34%)
		TM helix 4	197..218	CDD:320512	5/20 (25%)
		TM helix 5	251..280	CDD:320512	8/33 (24%)
		TM helix 6	299..329	CDD:320512	9/29 (31%)
		TM helix 7	342..367	CDD:320512	9/24 (38%)
prlh2r	NP_001108619.1	7tmA_PrRP_R	35..326	CDD:320516	76/312 (24%)
		TM helix 1	36..62	CDD:320516	4/25 (16%)
		TM helix 2	69..94	CDD:320516	9/28 (32%)
		TM helix 3	108..138	CDD:320516	10/29 (34%)
		TM helix 4	149..170	CDD:320516	5/20 (25%)
		TM helix 5	198..227	CDD:320516	7/28 (25%)
		TM helix 6	249..279	CDD:320516	9/29 (31%)
		TM helix 7	294..319	CDD:320516	9/24 (38%)