Protein Alignment TkR86C and Kiss1r

DIOPT Version :10

• Sequence 1: NP_001097741.1
• Gene: TkR86C / 41286
• FlyBaseID: FBgn0004841
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_076482.2
• Gene: Kiss1r / 78976
• RGDID: 70930
• Length: 396
• Species: Rattus norvegicus
• Alignment Length: 380
• Identity: 103/380 - (27%)
• Similarity: 170/380 - (44%)
• Gaps: 53/380 - (13%)

  Fly    70 PSPTRPYELPWEQKTIWAIIFGLMMFVAIAGNGIVLWIVTGHRSMRTVTNYFLLNLSIADLLMSS 134
            |.|...:.:|        :.|..:|.:.:.||.:|::::..|:.|:||||:::.||:..|  ::.
  Rat    37 PRPLDAWLVP--------LFFAALMLLGLVGNSLVIFVICRHKHMQTVTNFYIANLAATD--VTF 91

  Fly   135 LNCVFNFIFMLN--SDWPFGSIYCTINNFVANVTVSTSVFTLVAISFDRYIAIVHPLK---RRTS 194
            |.|...|..:|.  ..|..|...|...|::..|:|..:..||.|:|.||:...|.||:   |||.
  Rat    92 LLCCVPFTALLYPLPTWVLGDFMCKFVNYIQQVSVQATCATLTAMSVDRWYVTVFPLRALHRRTP 156

  Fly   195 RRKVRIILVLIWALSCVLSAPCLLYSSIMTKHYYNGKSRTVCFMMWPDGRYPTSMADYAYNLIIL 259
            |..:.:.| .||..|..:|||      ::..|..:....|.|...:|......:.|  .|||:.|
  Rat   157 RLALTVSL-SIWVGSAAVSAP------VLALHRLSPGPHTYCSEAFPSRALERAFA--LYNLLAL 212

  Fly   260 VLTYGIPMIVMLICYSLMGRVLWGSRSIGENTDRQMESM-------KSKRKVVRMFIAIVSIFAI 317
               |.:|::....||..|.|.|..:......||..::..       ..:.||.|:..|:|.:||.
  Rat   213 ---YLLPLLATCACYGAMLRHLGRAAVRPAPTDGALQGQLLAQRAGAVRTKVSRLVAAVVLLFAA 274

  Fly   318 CWLPYHLFFIY-------AYHNNQVASTKYVQHMYLGFYWLAMSNAMVNPLIYYWMNKRFRMYFQ 375
            ||.|..||.:.       |:|....|:  |...::.  :.::.||:.:|||:|.::...||..|.
  Rat   275 CWGPIQLFLVLQALGPSGAWHPRSYAA--YALKIWA--HCMSYSNSALNPLLYAFLGSHFRQAFC 335

  Fly   376 RIICCCCVGLTRHRFDSPKSRLTNKNS---SNRHTRGGYTVAHSLPNSSPPTTQT 427
            |:  |.| |..|.|  .|.:...:..:   |..|:|..:.|....|....|..::
  Rat   336 RV--CPC-GPQRQR--RPHASAHSDRAAPHSVPHSRAAHPVRVRTPEPGNPVVRS 385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR86C	NP_001097741.1	7tmA_TACR	84..374	CDD:320512	86/308 (28%)
		TM helix 1	85..111	CDD:320512	5/25 (20%)
		TM helix 2	118..144	CDD:320512	8/25 (32%)
		TM helix 3	156..186	CDD:320512	10/29 (34%)
		TM helix 4	197..218	CDD:320512	7/20 (35%)
		TM helix 5	251..280	CDD:320512	9/28 (32%)
		TM helix 6	299..329	CDD:320512	12/36 (33%)
		TM helix 7	342..367	CDD:320512	6/24 (25%)
Kiss1r	NP_076482.2	7tmA_KiSS1R	43..334	CDD:320223	87/316 (28%)
		TM helix 1	44..70	CDD:320223	6/33 (18%)
		TM helix 2	77..103	CDD:320223	8/27 (30%)
		TM helix 3	115..145	CDD:320223	10/29 (34%)
		TM helix 4	157..177	CDD:320223	8/26 (31%)
		TM helix 5	201..230	CDD:320223	10/33 (30%)
		TM helix 6	256..286	CDD:320223	12/29 (41%)
		TM helix 7	302..327	CDD:320223	7/26 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	346..396		8/42 (19%)