Protein Alignment TkR86C and npy5r

DIOPT Version :10

• Sequence 1: NP_001097741.1
• Gene: TkR86C / 41286
• FlyBaseID: FBgn0004841
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_001072244.1
• Gene: npy5r / 779693
• XenbaseID: XB-GENE-960863
• Length: 448
• Species: Xenopus tropicalis
• Alignment Length: 431
• Identity: 88/431 - (20%)
• Similarity: 159/431 - (36%)
• Gaps: 128/431 - (29%)

  Fly    71 SPTRPYELP-WEQ-----KTIWAIIFGLMMFVAI---AGNGIVLWIVTGHRSMRTVTNYFLLNLS 126
            |.||....| ||.     ..|...:.||..||::   .||.::|..:...|..:|:.||.:.||:
 Frog    21 SETRDSSFPEWEDYNSSVDDIRYFLIGLYTFVSLLGFMGNLLILLAIFKKRKQKTIINYLIGNLA 85

  Fly   127 IADLLMSSLNCVFNFIFMLNSDWPFGSIYCTINNFVANVTVSTSVFTLVAISFDRYIAIVHPLKR 191
            .:|:|:......|....:|...|.||.:.|.:..|:..|:|..|...|::|:..||..|.|||..
 Frog    86 FSDILVVLFCSPFTLTCVLLDQWIFGEVMCHVVPFLQCVSVLISTLMLMSIALVRYHMIKHPLST 150

  Fly   192 RTSRRKVRIILVLIWALSCVLSAPCLLYSSIMT-KHYYNGKS---RTVCFMMWPDGRYPTSMADY 252
            ..:......::..:|.|...:.:|..::..|:. :..:|..|   ..:|...||...|     ..
 Frog   151 NLTANHGYFLIATVWTLGFTICSPLPVFHKIINLREAFNLDSLINSYLCIESWPSDSY-----RI 210

  Fly   253 AYNLIILVLTYGIPMIVMLICYSLMGRVLWGSR------SIGEN--------------------- 290
            |:.:.:|::.|.:|:..:.|.::.:.|.: |||      .:.||
 Frog   211 AFTISLLLVQYILPLSCLTISHTSVCRSI-GSRLPSRDTKVEENEMINLTLQQPKNHRSELEISS 274

  Fly   291 --------------------------------------------TDR------------------ 293
                                                        |:|
 Frog   275 SRRWSYSCVRKHRRRYSKKSASVVPAILRRNQESNTGDIPETSMTERSHTLPSSVYLPGVPICFE 339

  Fly   294 -------QMESM------------KSKRKVVRMFIAIVSIFAICWLPYHLFFIYAYHNNQVASTK 339
                   :|.:|            :|:|...|:.|.|:: ||:.|:|.|||.:....|..:.|.:
 Frog   340 MKPEENSEMHNMISVSKSITRIRKRSRRVFCRLTILIIA-FAVSWMPLHLFHLVTDFNANLISNR 403

  Fly   340 YVQHMYLGFYWLAMSNAMVNPLIYYWMNKRFRMYFQRIICC 380
            :.:.:|...:.|.|.:..:||::|.::|...:.....:|.|
 Frog   404 HFKLVYCICHLLGMVSCCLNPILYGFLNDGIKADLMSLIKC 444

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR86C	NP_001097741.1	7tmA_TACR	84..374	CDD:320512	80/404 (20%)
		TM helix 1	85..111	CDD:320512	8/28 (29%)
		TM helix 2	118..144	CDD:320512	7/25 (28%)
		TM helix 3	156..186	CDD:320512	9/29 (31%)
		TM helix 4	197..218	CDD:320512	3/20 (15%)
		TM helix 5	251..280	CDD:320512	5/28 (18%)
		TM helix 6	299..329	CDD:320512	12/29 (41%)
		TM helix 7	342..367	CDD:320512	6/24 (25%)
npy5r	NP_001072244.1	7tmA_NPY5R	43..438	CDD:320520	79/401 (20%)
		TM helix 1	44..70	CDD:320520	7/25 (28%)
		TM helix 2	77..102	CDD:320520	7/24 (29%)
		TM helix 3	115..145	CDD:320520	9/29 (31%)
		TM helix 4	156..177	CDD:320520	3/20 (15%)
		TM helix 5	209..238	CDD:320520	5/28 (18%)
		TM helix 6	363..393	CDD:320520	12/30 (40%)
		TM helix 7	406..431	CDD:320520	6/24 (25%)