DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment TkR86C and Gpr17

DIOPT Version :9

Sequence 1:	NP_001097741.1	Gene:	TkR86C / 41286	FlyBaseID:	FBgn0004841	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	NP_001065245.1	Gene:	Gpr17 / 767613	RGDID:	1589785	Length:	339	Species:	Rattus norvegicus

Alignment Length:	326	Identity:	86/326 - (26%)
Similarity:	146/326 - (44%)	Gaps:	61/326 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 ELPWEQKTIWAIIFGLMMFVAIAGNGIVLWIVTGHRSMRTVTNYFLLNLSIADL---LMSSLNCV 138
            |.|.| ..::|..:.|...:|..||.:.||:........|..|.||::|::|||   |:.....|
  Rat    26 ETPLE-NMLFACFYLLDFILAFVGNALALWLFIWDHKSGTPANVFLMHLAVADLSCVLVLPTRLV 89

  Fly   139 FNFIFMLNSDWPFGSIYCTINNFVANVTVSTSVFTLVAISFDRYIAIVHPLKRRTSRRKV--RII 201
            ::|   ..:.||||.|.|.:..|:..:.:..|::.|..||.||::|||||:|....||.:  .:.
  Rat    90 YHF---SGNHWPFGEIPCRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLYAHLA 151

  Fly   202 LVLIWALSCVLSAPCLLY-SSIMTKHYYNGKSRTVCFMMWPDGRYPTSMADYAYNLIILVLTYGI 265
            ...:|.:..|..||.|:. .::.|.|      ..||..:     |....:.:|  |..|.:.:..
  Rat   152 CAFLWIVVAVAMAPLLVSPQTVQTNH------TVVCLQL-----YREKASHHA--LASLAVAFTF 203

  Fly   266 PMIVMLICYSLMGRVLWGSRSIGENTDRQMESMKSKRKVVRMFIAIVSIFAICWLPYHLF-FIYA 329
            |.|..:.||.|:.|    |...|...::.:     |.|.|||...:::||.||::|||:. .:|.
  Rat   204 PFITTVTCYLLIIR----SLRQGPRIEKHL-----KNKAVRMIAMVLAIFLICFVPYHIHRSVYV 259

  Fly   330 YH----------------NNQVASTKYVQHMYLGFYWLAMSNAMVNPLIYYWMNKRFRMYFQRII 378
            .|                .|::.|.            |...|..::|::|:::.::||.....::
  Rat   260 LHYRGGGTSCSAQRALALGNRITSC------------LTSLNGALDPVMYFFVAEKFRHALCNLL 312

  Fly   379 C 379
            |
  Rat   313 C 313

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TkR86C	NP_001097741.1	7tm_4	92..376	CDD:304433	81/306 (26%)
TkR86C	NP_001097741.1	7tm_1	100..363	CDD:278431	76/285 (27%)
Gpr17	NP_001065245.1	7tmA_GPR17	32..308	CDD:320289	82/312 (26%)
		TM helix 1	34..58	CDD:320289	7/23 (30%)
		TM helix 2	67..88	CDD:320289	8/20 (40%)
		TM helix 3	105..127	CDD:320289	4/21 (19%)
		TM helix 4	150..166	CDD:320289	3/15 (20%)
		TM helix 5	190..213	CDD:320289	6/24 (25%)
		TM helix 6	234..256	CDD:320289	10/21 (48%)
		TM helix 7	276..301	CDD:320289	6/36 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000