Protein Alignment TkR86C and Gpr165

DIOPT Version :10

• Sequence 1: NP_001097741.1
• Gene: TkR86C / 41286
• FlyBaseID: FBgn0004841
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_083812.1
• Gene: Gpr165 / 76206
• MGIID: 1923456
• Length: 455
• Species: Mus musculus
• Alignment Length: 456
• Identity: 98/456 - (21%)
• Similarity: 206/456 - (45%)
• Gaps: 68/456 - (14%)

  Fly    23 LNSIVNTTLLGSLN--RTEVVSLLSSIIDNRDNLESINEAKDFLTECLFPSPTRPYELPW----E 81
            :.|..:..|..:.|  |..::|.:..:.|:..|...:.:.            :.|.:|..    |
Mouse    40 ITSTTSQVLQAASNAGRNGMLSKMDKLADHMSNSGDLADT------------SGPLDLEIVSQDE 92

  Fly    82 QKTIWAII-FGLMMFVAIAGNGIVLWIVTGHRSMRTVTNYFLLNLSIADLLMSSLNCVFNFIFML 145
            |...|.:: :.:::|.||.||.::..|:..::.:.|.|..|::|:|:.:::::.|:..|..:..|
Mouse    93 QVQFWLVVGYTIVVFAAIIGNWVLNHIIMKYKRVHTATGLFVVNISVTNMMLALLSSPFTMVRYL 157

  Fly   146 NSDWPFGSIYCTINNFVANVTVSTSVFTLVAISFDRYIAIVHPLKRRTSRRKVRIILVLIWALSC 210
            .:...||.:.|.::.|........:|.::.|||.||:..:::|||.|.:..:..:.:::||.:|.
Mouse   158 CNSLVFGKMTCHLSRFAQYSCAYVTVMSMAAISLDRHRVMLYPLKARITPMQGNVCIIIIWIVST 222

  Fly   211 VLSAPCLLYSSIMTKHYYNGKSRTVCFMMWPDGRYPTSMADYAY-NLIILVLTYGIPMIVMLICY 274
            ..:.|..:|..:....:.|....:.|...:|   | ||.:.:.| :|...:|.:.:|::|::..|
Mouse   223 CAALPHAVYQKLYQVEFGNTTEESACLPSFP---Y-TSKSTWKYLDLGTFLLFFILPLLVLVAVY 283

  Fly   275 SLMGRVLWGSRSIGE-NTDRQMESMKSKRKVVRMFIAIVSIFAICWLPYHLFFIYAYHNNQVAST 338
            ..:.:.||...::.: |....:.....|::.::|.:.:|.::.|.|||.:::.:.      ::|.
Mouse   284 GHVAKKLWIHDAVDDINIHTYICQRGKKKQTLKMLMTVVLLYTISWLPLNVYLVL------LSSE 342

  Fly   339 KYVQH--MYLGFYWLAMSNAMVNPLIYYWMNKRFRMYFQRIICCCCVGLTRHRFDSPKSRLTNKN 401
            ....|  :|...:|||:|::..||.||.|::..||:..|::|    :.:.:...|. .|||..::
Mouse   343 SISSHNGLYFFLHWLAISSSCYNPYIYCWLSDSFRIEVQKVI----MEIQKMLLDK-ISRLRGEH 402

  Fly   402 S-----SNRHTRGGYTVAHSLPN----------SSPPTTQTLLAVLAQTLTQPKPQTQLLLSHHS 451
            .     |:..|.|.......:|.          .|||               |.|..::...|..
Mouse   403 RRLSSVSHSQTPGSVDPNPGVPKFPRFRDFDELPSPP---------------PSPTVEISFLHSV 452

  Fly   452 P 452
            |
Mouse   453 P 453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR86C	NP_001097741.1	7tmA_TACR	84..374	CDD:320512	70/294 (24%)
		TM helix 1	85..111	CDD:320512	7/26 (27%)
		TM helix 2	118..144	CDD:320512	6/25 (24%)
		TM helix 3	156..186	CDD:320512	8/29 (28%)
		TM helix 4	197..218	CDD:320512	4/20 (20%)
		TM helix 5	251..280	CDD:320512	6/29 (21%)
		TM helix 6	299..329	CDD:320512	7/29 (24%)
		TM helix 7	342..367	CDD:320512	11/26 (42%)
Gpr165	NP_083812.1	7tmA_GPR83	96..380	CDD:320511	70/293 (24%)
		TM helix 1	97..123	CDD:320511	7/25 (28%)
		TM helix 2	130..155	CDD:320511	6/24 (25%)
		TM helix 3	168..198	CDD:320511	8/29 (28%)
		TM helix 4	209..230	CDD:320511	4/20 (20%)
		TM helix 5	260..289	CDD:320511	6/28 (21%)
		TM helix 6	309..339	CDD:320511	7/35 (20%)
		TM helix 7	348..373	CDD:320511	10/24 (42%)