Protein Alignment TkR86C and Npffr1

DIOPT Version :10

• Sequence 1: NP_001097741.1
• Gene: TkR86C / 41286
• FlyBaseID: FBgn0004841
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: XP_006256547.1
• Gene: Npffr1 / 64107
• RGDID: 621570
• Length: 468
• Species: Rattus norvegicus
• Alignment Length: 312
• Identity: 84/312 - (26%)
• Similarity: 154/312 - (49%)
• Gaps: 48/312 - (15%)

  Fly    92 LMMFVAIAGNGIVLWIVTGHRSMRTVTNYFLLNLSIADLLMSSLNCVFNFIFMLNSDWPFGSIYC 156
            |:..:.:.||.:|.:||..:|.||||||.|:|||:::|||:.........:..|.:.|||.:..|
  Rat    88 LIFLLCMVGNTLVCFIVLKNRHMRTVTNMFILNLAVSDLLVGIFCMPTTLVDNLITGWPFDNATC 152

  Fly   157 TINNFVANVTVSTSVFTLVAISFDRYIAIVHPLKRRTSRRKVRIILVLIWALSCVLSAPCLLYSS 221
            .::..|..::||.||||||||:.:|:..||||.:.:.:.||....:.:||||:.::..|..:..:
  Rat   153 KMSGLVQGMSVSASVFTLVAIAVERFRCIVHPFREKLTLRKALFTIAVIWALALLIMCPSAVTLT 217

  Fly   222 IMTKHYY---NGKSRTV----CFMMWPDGRYPTSMADYAYNLIILVLTYGIPMIVMLICYSLMGR 279
            :..:.::   :.::|:.    |:..||:    ..|.. .|..::....|.:|:.::::.|..:.|
  Rat   218 VTREEHHFMLDARNRSYPLYSCWEAWPE----KGMRK-VYTAVLFAHIYLVPLALIVVMYVRIAR 277

  Fly   280 VLWGSRSIGENTDRQM----ESMKSKRKVVRMFIAIVSIFAICWLP-----------------YH 323
            .|..:.....:|:..:    .:.:.:.:||.|.:.:...|.:.|||                 .|
  Rat   278 KLCQAPGPARDTEEAVAEGGRTSRRRARVVHMLVMVALFFTLSWLPLWVLLLLIDYGELSELQLH 342

  Fly   324 LFFIYAYHNNQVASTKYVQHMYLGFYWLAMSNAMVNPLIYYWMNKRFRMYFQ 375
            |..:||:   .:|            :|||..::..||:||.:.|:.||..||
  Rat   343 LLSVYAF---PLA------------HWLAFFHSSANPIIYGYFNENFRRGFQ 379

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR86C	NP_001097741.1	7tmA_TACR	84..374	CDD:320512	82/309 (27%)
		TM helix 1	85..111	CDD:320512	6/18 (33%)
		TM helix 2	118..144	CDD:320512	9/25 (36%)
		TM helix 3	156..186	CDD:320512	13/29 (45%)
		TM helix 4	197..218	CDD:320512	6/20 (30%)
		TM helix 5	251..280	CDD:320512	4/28 (14%)
		TM helix 6	299..329	CDD:320512	9/46 (20%)
		TM helix 7	342..367	CDD:320512	7/24 (29%)
Npffr1	XP_006256547.1	7tmA_NPFFR1	80..378	CDD:320647	82/309 (27%)
		TM helix 1	81..107	CDD:320647	6/18 (33%)
		TM helix 2	114..140	CDD:320647	9/25 (36%)
		TM helix 3	152..182	CDD:320647	13/29 (45%)
		TM helix 4	193..214	CDD:320647	6/20 (30%)
		TM helix 5	249..278	CDD:320647	4/29 (14%)
		TM helix 6	301..331	CDD:320647	7/29 (24%)
		TM helix 7	346..371	CDD:320647	10/39 (26%)