DRSC/TRiP Functional Genomics Resources

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Protein Alignment TkR86C and CYSLTR2

DIOPT Version :9

Sequence 1:NP_001097741.1 Gene:TkR86C / 41286 FlyBaseID:FBgn0004841 Length:555 Species:Drosophila melanogaster
Sequence 2:NP_001295394.1 Gene:CYSLTR2 / 57105 HGNCID:18274 Length:346 Species:Homo sapiens


Alignment Length:296 Identity:88/296 - (29%)
Similarity:140/296 - (47%) Gaps:25/296 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly    82 QKTIWAIIFGLMMFVAIAGNGIVLWIVTGHRSMRTVTNYFLLNLSIADLLMSSLNCVFNFIFMLN 146
            ::..:.|::.::.|..:.|||:.:::........|..|.|:|||:|:|||..|........::..
Human    37 KREFFPIVYLIIFFWGVLGNGLSIYVFLQPYKKSTSVNVFMLNLAISDLLFISTLPFRADYYLRG 101

  Fly   147 SDWPFGSIYCTINNFVANVTVSTSVFTLVAISFDRYIAIVHP--LKRRTSRRKVRIILVLIWALS 209
            |:|.||.:.|.|.::...|.:.:|::.|..:|..|::|:|||  |...||.|...|:..:||.| 
Human   102 SNWIFGDLACRIMSYSLYVNMYSSIYFLTVLSVVRFLAMVHPFRLLHVTSIRSAWILCGIIWIL- 165

  Fly   210 CVLSAPCLLYSSIM---TKHYYNGKSRTVCFMMWPDGRYPTSMADYAYNLIILVLTYGIPMIVML 271
                   ::.||||   :....|| |.|.|..:   ..|..:... ..|.|.||:...:|...:.
Human   166 -------IMASSIMLLDSGSEQNG-SVTSCLEL---NLYKIAKLQ-TMNYIALVVGCLLPFFTLS 218

  Fly   272 ICYSLMGRVLWGSRSIGENTDRQMESMKSKRKVVRMFIAIVSIFAICWLPYHLFFIYAYHNNQVA 336
            |||.|:.|||. ...:.|:..|     .|.||.:...|..:.||.:|:||||..........:|.
Human   219 ICYLLIIRVLL-KVEVPESGLR-----VSHRKALTTIIITLIIFFLCFLPYHTLRTVHLTTWKVG 277

  Fly   337 STKYVQHMYLGF-YWLAMSNAMVNPLIYYWMNKRFR 371
            ..|...|..|.. ..||.:||..|||:||:..:.|:
Human   278 LCKDRLHKALVITLALAAANACFNPLLYYFAGENFK 313

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
TkR86CNP_001097741.1 7tm_4 92..376 CDD:304433 87/286 (30%)
7tm_1 100..363 CDD:278431 83/268 (31%)
CYSLTR2NP_001295394.1 7tmA_CysLTR2 39..316 CDD:320285 88/294 (30%)
TM helix 1 41..65 CDD:320285 5/23 (22%)
TM helix 2 74..95 CDD:320285 10/20 (50%)
TM helix 3 112..134 CDD:320285 4/21 (19%)
TM helix 4 157..173 CDD:320285 7/23 (30%)
TM helix 5 199..222 CDD:320285 7/23 (30%)
TM helix 6 246..268 CDD:320285 8/21 (38%)
TM helix 7 284..309 CDD:320285 11/24 (46%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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