Protein Alignment TkR86C and npffr1l2

DIOPT Version :10

• Sequence 1: NP_001097741.1
• Gene: TkR86C / 41286
• FlyBaseID: FBgn0004841
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_001165168.1
• Gene: npffr1l2 / 570189
• ZFINID: ZDB-GENE-060526-110
• Length: 484
• Species: Danio rerio
• Alignment Length: 391
• Identity: 112/391 - (28%)
• Similarity: 177/391 - (45%)
• Gaps: 53/391 - (13%)

  Fly    72 PTRPYELPWEQKTIWAIIFGLMMFVAIAGNGIVLWIVTGHRSMRTVTNYFLLNLSIADLLMSSLN 136
            |...:.||.......|.:|  :..:.:.|||:|..||..:|.||||||.|:|||:::|||:....
Zfish    43 PYYQHSLPVAAALTLAYLF--IFLLCMVGNGLVCLIVLENRRMRTVTNLFILNLAVSDLLVGVFC 105

  Fly   137 CVFNFIFMLNSDWPFGSIYCTINNFVANVTVSTSVFTLVAISFDRYIAIVHPLKRRTSRRKVRII 201
            .....:..|.:.|||.:..|.::..|..::||.||||||||:.||:..||:|.:.:.:....::.
Zfish   106 IPTTLVDNLITGWPFTNTVCKMSGLVQGMSVSASVFTLVAIAVDRFRCIVYPFQPKLTLLVAKVT 170

  Fly   202 LVLIWALSCVLSAPCLLYSSI-MTKHYYNGKSRTV--------CFMMW--PDGRYPTSMADYAYN 255
            :|:||.|:.|:..|..:..:: ..:|:|..:....        ||..|  |..|       ..|.
Zfish   171 IVMIWVLAVVIMCPSAVTLTVERVEHHYMVRGEDYNHTYPLFSCFENWANPQMR-------KVYT 228

  Fly   256 LIILVLTYGIPMIVMLICYSLMGRVLWGSRSI-------------------GENTDRQMESMKSK 301
            .::....|.||:.::.:.|..:|..|:.:..|                   |:...|.:.|.| |
Zfish   229 TVLFAHIYLIPLTLITLMYGRIGIKLYTTSVISGNDQHDGGQPHTSPQAPGGQQEGRPLISQK-K 292

  Fly   302 RKVVRMFIAIVSIFAICWLP-YHLFFIYAYHNNQVASTKYVQHMYLGF-YWLAMSNAMVNPLIYY 364
            .||::|...:..:|.|.||| :.|..:..|........:.:......| :|||.||:.|||:||.
Zfish   293 IKVIKMLSIVALLFTISWLPLWTLMLLTDYGGLNEDELELLSGYVFPFAHWLAFSNSSVNPIIYG 357

  Fly   365 WMNKRFRMYFQRIIC----CCCVGLTRHRFDSPKSR------LTNKNSSNRHTRGGYTVAHSLPN 419
            :.|:.|:..|| .:|    ||..|:|..|....|:|      ..|.|..|...|........|.|
Zfish   358 YYNENFKRGFQ-AVCRAHSCCFEGMTARRGMRRKARGETRDPAVNSNPLNFGARNRVYTDGDLKN 421

  Fly   420 S 420
            |
Zfish   422 S 422

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR86C	NP_001097741.1	7tmA_TACR	84..374	CDD:320512	92/321 (29%)
		TM helix 1	85..111	CDD:320512	8/25 (32%)
		TM helix 2	118..144	CDD:320512	9/25 (36%)
		TM helix 3	156..186	CDD:320512	14/29 (48%)
		TM helix 4	197..218	CDD:320512	6/20 (30%)
		TM helix 5	251..280	CDD:320512	6/28 (21%)
		TM helix 6	299..329	CDD:320512	11/30 (37%)
		TM helix 7	342..367	CDD:320512	11/25 (44%)
npffr1l2	NP_001165168.1	7tmA_NPFFR1	53..367	CDD:320647	92/323 (28%)
		TM helix 1	54..80	CDD:320647	8/27 (30%)
		TM helix 2	87..113	CDD:320647	9/25 (36%)
		TM helix 3	125..155	CDD:320647	14/29 (48%)
		TM helix 4	166..187	CDD:320647	6/20 (30%)
		TM helix 5	224..253	CDD:320647	7/35 (20%)
		TM helix 6	290..320	CDD:320647	11/30 (37%)
		TM helix 7	335..360	CDD:320647	11/24 (46%)