Protein Alignment TkR86C and grpr

DIOPT Version :10

• Sequence 1: NP_001097741.1
• Gene: TkR86C / 41286
• FlyBaseID: FBgn0004841
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: XP_695673.2
• Gene: grpr / 567289
• ZFINID: ZDB-GENE-081015-4
• Length: 376
• Species: Danio rerio
• Alignment Length: 358
• Identity: 103/358 - (28%)
• Similarity: 176/358 - (49%)
• Gaps: 50/358 - (13%)

  Fly    85 IWAIIFGLMMFVAIAGNGIVLWIVTGHRSMRTVTNYFLLNLSIADLLMSSLNCVFNFIFMLNSDW 149
            |.|.::.|::...:.||..::......:|||.|.|.|:.:|::.|:|:.......:....|..:|
Zfish    36 IIATVYALLITAGLIGNVTLIRTFCIVKSMRNVPNLFMSSLALGDVLLLVTCAPVDASKFLADEW 100

  Fly   150 PFGSIYCTINNFVANVTVSTSVFTLVAISFDRYIAIVHPLKRRTSRRKVRIIL--VLIWALSCVL 212
            .||.:.|.:..|:...:|..|||||.|::.|||.|||.|:..::|:..:::.|  ..||.||.||
Zfish   101 LFGRMGCKLIPFIQLTSVGVSVFTLTALAADRYKAIVKPMDIQSSKASLKVCLRAASIWMLSMVL 165

  Fly   213 SAPCLLYSSIMTKHY-YNGKSRTVCFMMWPDGRYP---------TSMADYAYNLIILVLTYGIPM 267
            :.|..::|.:.|.|. ...::...|      ..||         .|||.:       ::.|.||:
Zfish   166 AIPEAVFSDLHTFHIPQTNETFKTC------APYPHAGDLHPKIHSMASF-------LILYIIPL 217

  Fly   268 IVMLICYSLMGRVLWGSRS---IGENTD--RQMESMKSKRKVVRMFIAIVSIFAICWLPYHLFFI 327
            .::.:.|..:.|.|..|.:   :..||.  ||:||.....|.|.:|   |.:|||||||.|:.::
Zfish   218 FIISVYYIFIARSLIQSANNMPVEGNTHIRRQVESRMRLAKTVLVF---VGLFAICWLPNHVIYL 279

  Fly   328 Y-AYHNNQVASTKYVQHMYLGF--YWLAMSNAMVNPLIYYWMNKRFRMYFQRIICCCCVGLT--- 386
            | :||..:|.::  :.|.....  ..||.:|:.|||...|.::|.||..|.:.:||||..::
Zfish   280 YRSYHYTEVDTS--MAHFIASVCARILAFTNSCVNPFALYLLSKSFRKQFNKQLCCCCPSISLRS 342

  Fly   387 ----RHRFDSPKSRLTNKNSSNRHTRGGYTVAH 415
                ||     .:||::..|:..|:...:::.:
Zfish   343 QSSRRH-----NTRLSSLKSTQNHSVASFSLVN 370

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR86C	NP_001097741.1	7tmA_TACR	84..374	CDD:320512	92/308 (30%)
		TM helix 1	85..111	CDD:320512	5/25 (20%)
		TM helix 2	118..144	CDD:320512	5/25 (20%)
		TM helix 3	156..186	CDD:320512	13/29 (45%)
		TM helix 4	197..218	CDD:320512	8/22 (36%)
		TM helix 5	251..280	CDD:320512	4/28 (14%)
		TM helix 6	299..329	CDD:320512	13/30 (43%)
		TM helix 7	342..367	CDD:320512	8/26 (31%)
grpr	XP_695673.2	7tm_GPCRs	37..327	CDD:475119	91/307 (30%)
		TM helix 1	37..61	CDD:410628	4/23 (17%)
		TM helix 2	70..92	CDD:410628	5/21 (24%)
		TM helix 3	108..130	CDD:410628	8/21 (38%)
		TM helix 4	153..169	CDD:410628	7/15 (47%)
		TM helix 5	202..225	CDD:410628	6/29 (21%)
		TM helix 6	257..279	CDD:410628	12/24 (50%)
		TM helix 7	295..320	CDD:410628	7/24 (29%)