Protein Alignment TkR86C and kiss1ra

DIOPT Version :10

• Sequence 1: NP_001097741.1
• Gene: TkR86C / 41286
• FlyBaseID: FBgn0004841
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_001099149.2
• Gene: kiss1ra / 561898
• ZFINID: ZDB-GENE-070912-521
• Length: 366
• Species: Danio rerio
• Alignment Length: 385
• Identity: 107/385 - (27%)
• Similarity: 170/385 - (44%)
• Gaps: 74/385 - (19%)

  Fly    45 SSIIDNRDNLESINEAKD----FLTECLFPSPTRPYELPWEQKTIWAIIFGLMMFVAIAGNGIVL 105
            |.:::......|:.:::|    |||:.            |    :..:.|.|:|.|.:.||.:|:
Zfish    10 SELLNGSFRNSSMEDSEDGEHPFLTDA------------W----LVPLFFSLIMLVGLIGNSLVI 58

  Fly   106 WIVTGHRSMRTVTNYFLLNLSIADLLMSSLNCVFNFIFMLN--SDWPFGSIYCTINNFVANVTVS 168
            ::::.||.|||.||:::.||:..|::.  |.|...|...|.  ..|.||...|....|:..|||.
Zfish    59 YVISKHRQMRTATNFYIANLAATDIIF--LLCCVPFTATLYPLPGWIFGDFMCKFVAFLQQVTVQ 121

  Fly   169 TSVFTLVAISFDRYIAIVHPLKRRTSR--RKVRIILVLIWALSCVLSAPCLLYSSIMTKHYYNGK 231
            .:..||.|:|.||....|:|||....|  |...|:.:.||..|.:||.|..||..:...::|.
Zfish   122 ATCITLTAMSGDRCYVTVYPLKSLHHRTPRVAMIVSICIWIGSFILSIPIFLYQRLEDGYWYG-- 184

  Fly   232 SRTVCFMMWPDGRYPTSMADYAYNLIILVLTYGIPMIVMLICYSLM-GRVLWGSRSIGENTDRQM 295
            .|..|.     .|:|:...:.|:.|...:..|.:|:|.:..|||.| .||  |..|:....:...
Zfish   185 PRKYCM-----ERFPSKTHEKAFILYQFIAVYLLPVITISFCYSFMLKRV--GQASVEPVDNNHQ 242

  Fly   296 ESMKSKR------KVVRMFIAIVSIFAICWLPYHLFFIYAYHNNQVASTKYVQHMYLGF------ 348
            ..:.|:|      |:.:|.:.||.:|.|||.|..:|.::             |..|..|
Zfish   243 VHLLSERTISIRSKISKMVVVIVVLFTICWGPIQIFVLF-------------QSFYPNFKANYAT 294

  Fly   349 ----YW---LAMSNAMVNPLIYYWMNKRFRMYFQRIICCCCVGLTRH--RFDSPKSRLTN 399
                .|   ::.:|:.:||::|.:|...||..|::..    ..|.||  |..|..||..|
Zfish   295 YKIKTWANCMSYANSSINPIVYGFMGASFRKSFRKTF----PFLFRHKVRDSSVASRTAN 350

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR86C	NP_001097741.1	7tmA_TACR	84..374	CDD:320512	91/313 (29%)
		TM helix 1	85..111	CDD:320512	7/25 (28%)
		TM helix 2	118..144	CDD:320512	8/25 (32%)
		TM helix 3	156..186	CDD:320512	11/29 (38%)
		TM helix 4	197..218	CDD:320512	7/20 (35%)
		TM helix 5	251..280	CDD:320512	9/29 (31%)
		TM helix 6	299..329	CDD:320512	12/35 (34%)
		TM helix 7	342..367	CDD:320512	8/37 (22%)
kiss1ra	NP_001099149.2	7tmA_KiSS1R	37..327	CDD:320223	92/317 (29%)
		TM helix 1	38..64	CDD:320223	7/25 (28%)
		TM helix 2	71..97	CDD:320223	8/27 (30%)
		TM helix 3	109..139	CDD:320223	11/29 (38%)
		TM helix 4	151..171	CDD:320223	7/19 (37%)
		TM helix 5	199..228	CDD:320223	9/28 (32%)
		TM helix 6	252..282	CDD:320223	10/42 (24%)
		TM helix 7	295..320	CDD:320223	5/24 (21%)