Protein Alignment TkR86C and nmbr

DIOPT Version :10

• Sequence 1: NP_001097741.1
• Gene: TkR86C / 41286
• FlyBaseID: FBgn0004841
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: XP_690325.2
• Gene: nmbr / 561834
• ZFINID: ZDB-GENE-041014-369
• Length: 372
• Species: Danio rerio
• Alignment Length: 380
• Identity: 98/380 - (25%)
• Similarity: 184/380 - (48%)
• Gaps: 62/380 - (16%)

  Fly    59 EAKDFLTECLFPSPTRPYELPWEQKTIWAIIFGLMMFVAIAGNGIVLWIVTGHRSMRTVTNYFLL 123
            |...|:.:|:.||                 ::.|::.|.:.||..::.|.....:||:|.|.|:.
Zfish    25 ETVHFIIQCVIPS-----------------VYILIITVGLLGNITLVKIFITTSAMRSVPNIFIS 72

  Fly   124 NLSIADLLMSSLNCV----FNFIFMLNSDWPFGSIYCTINNFVANVTVSTSVFTLVAISFDRYIA 184
            :|::.|||: .:.||    |.:.:   .:|.||::.|.:...:...:|..|||||.|:|.||:.|
Zfish    73 SLAVGDLLL-LVTCVPVDAFRYFY---EEWIFGTVACKMIPVIQLTSVGVSVFTLTALSADRHKA 133

  Fly   185 IVHPLKRRTSRRKVRIIL--VLIWALSCVLSAPCLLYSSIMTKHYYNGKSRTVCFMMWPDGRYPT 247
            ||:|:..::|.......|  :.||.:|.:|:.|..::|.::.....| .:.|.|.      .||.
Zfish   134 IVNPMDIQSSSAVFWTCLKAITIWVVSVLLAIPEAVFSQVVHMPDKN-TTFTACV------PYPL 191

  Fly   248 S--MADYAYNLIILVLTYGIPMIVMLICYSLMGRVLWGSR-----SIGENTDRQMESMKSKRKVV 305
            |  |....::::|.::.:.||:.::.:.|..:.|.|..|.     .|.|::.||.|:.|...|:|
Zfish   192 SNEMHPKIHSIMIFLVYFLIPLSIISVYYYHIARTLIKSAHDMPGEISEHSKRQTETRKRLAKIV 256

  Fly   306 RMFIAIVSIFAICWLPYHLFFIY-AYHNNQVASTKYVQHMYLGFY--WLAMSNAMVNPLIYYWMN 367
            .:|   |.:||:||.|.|:.::| :::..|:.|:  :.|:.:...  .|:.|::.|||...|.::
Zfish   257 LVF---VGLFALCWFPNHVLYMYRSFNYRQIDSS--LSHLIITLVARVLSFSSSCVNPFALYLLS 316

  Fly   368 KRFRMYFQRIICCCCVGLTRHRFDSPKSRLTNKNSSNRHTRGGYTVAHSLPNSSP 422
            :.||.:|...:.|     .:.::....:......|:.|.|        |:..|:|
Zfish   317 ESFRRHFNNQLLC-----RQRKYQERNTSYLQSTSAIRMT--------SIRKSTP 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR86C	NP_001097741.1	7tmA_TACR	84..374	CDD:320512	85/305 (28%)
		TM helix 1	85..111	CDD:320512	5/25 (20%)
		TM helix 2	118..144	CDD:320512	9/29 (31%)
		TM helix 3	156..186	CDD:320512	12/29 (41%)
		TM helix 4	197..218	CDD:320512	6/22 (27%)
		TM helix 5	251..280	CDD:320512	4/28 (14%)
		TM helix 6	299..329	CDD:320512	12/30 (40%)
		TM helix 7	342..367	CDD:320512	7/26 (27%)
nmbr	XP_690325.2	7tm_GPCRs	33..323	CDD:475119	88/322 (27%)
		TM helix 1	35..59	CDD:410628	7/40 (18%)
		TM helix 2	68..90	CDD:410628	8/22 (36%)
		TM helix 3	106..128	CDD:410628	7/21 (33%)
		TM helix 4	151..167	CDD:410628	5/15 (33%)
		TM helix 5	198..221	CDD:410628	3/22 (14%)
		TM helix 6	253..275	CDD:410628	10/24 (42%)
		TM helix 7	291..316	CDD:410628	6/24 (25%)