Protein Alignment TkR86C and npffr1l1

DIOPT Version :10

• Sequence 1: NP_001097741.1
• Gene: TkR86C / 41286
• FlyBaseID: FBgn0004841
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_001165167.1
• Gene: npffr1l1 / 559950
• ZFINID: ZDB-GENE-091118-18
• Length: 398
• Species: Danio rerio
• Alignment Length: 326
• Identity: 100/326 - (30%)
• Similarity: 159/326 - (48%)
• Gaps: 36/326 - (11%)

  Fly    78 LPWEQKTI-------------WAIIFGLMMFVAIAGNGIVLWIVTGHRSMRTVTNYFLLNLSIAD 129
            |.|:..|:             :.:.:.|::.:.:.|||:|..:|..:|:||:|||.|:|||:::|
Zfish    13 LSWQNCTLLPYYIHSAGMAVSYILSYLLVLLLCVVGNGLVCLVVIRNRNMRSVTNLFILNLAVSD 77

  Fly   130 LLMSSLNCVFNFIFMLNSDWPFGSIYCTINNFVANVTVSTSVFTLVAISFDRYIAIVHPLKRRTS 194
            ||:.........|..|.|.|||..|.||::|.|..::||.||||||||:.||:..||:|...|..
Zfish    78 LLVGIFCVPTTLIDSLISGWPFSQITCTMSNLVQGMSVSASVFTLVAIAVDRFTGIVYPFHHRLR 142

  Fly   195 RRKVRIILVLIWALSCVLSAPCLLYSSI--MTKHYYNGKSRT----VCFMMWPDGRYPTSMADY- 252
            .......:|.||.|:..:..|.....::  :...|.....:.    |||..||       .||.
Zfish   143 PVTALFAIVFIWLLAFAIIFPSAATLTVIHLDDMYMVQNDQIYPLFVCFEDWP-------RADMR 200

  Fly   253 -AYNLIILVLTYGIPMIVMLICYSLMGRVLWGSRSIGENTDRQMESMKSKRKVVRMFIAIVSIFA 316
             .|..:|.|..|..|:.::.|.|..:...|  |.::.||..|....|    ||::|.|.:..:|.
Zfish   201 RVYTTVIFVHVYLAPLGLISIMYGCIAAKL--SSNLQENRLRSRRRM----KVIKMLIMVAVLFM 259

  Fly   317 ICWLP-YHLFFIYAYHNNQVASTKYV-QHMYLGFYWLAMSNAMVNPLIYYWMNKRFRMYFQRIIC 379
            :.||| :.|..:..|.:.......:: .:::...:|||..|:.|||:||.:.|:.||..||..:.
Zfish   260 VSWLPLWTLMLLTDYQDLDRQQIDFLSSYLFPVAHWLAFFNSGVNPIIYGFFNENFRRGFQAAVA 324

  Fly   380 C 380
            |
Zfish   325 C 325

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR86C	NP_001097741.1	7tmA_TACR	84..374	CDD:320512	95/312 (30%)
		TM helix 1	85..111	CDD:320512	6/38 (16%)
		TM helix 2	118..144	CDD:320512	10/25 (40%)
		TM helix 3	156..186	CDD:320512	16/29 (55%)
		TM helix 4	197..218	CDD:320512	5/20 (25%)
		TM helix 5	251..280	CDD:320512	8/30 (27%)
		TM helix 6	299..329	CDD:320512	9/30 (30%)
		TM helix 7	342..367	CDD:320512	9/24 (38%)
npffr1l1	NP_001165167.1	7tm_GPCRs	32..319	CDD:475119	94/299 (31%)
		TM helix 1	34..58	CDD:320647	6/23 (26%)
		TM helix 2	67..89	CDD:320647	8/21 (38%)
		TM helix 3	105..127	CDD:320647	13/21 (62%)
		TM helix 4	148..164	CDD:320647	4/15 (27%)
		TM helix 5	201..224	CDD:320647	6/22 (27%)
		TM helix 6	248..270	CDD:320647	7/21 (33%)
		TM helix 7	287..312	CDD:320647	9/24 (38%)