Protein Alignment TkR86C and tacr3a

DIOPT Version :10

• Sequence 1: NP_001097741.1
• Gene: TkR86C / 41286
• FlyBaseID: FBgn0004841
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_001243567.1
• Gene: tacr3a / 555482
• ZFINID: ZDB-GENE-090312-106
• Length: 399
• Species: Danio rerio
• Alignment Length: 390
• Identity: 139/390 - (35%)
• Similarity: 224/390 - (57%)
• Gaps: 31/390 - (7%)

  Fly    79 PWEQKTIWAIIFGLMMFVAIAGNGIVLWIVTGHRSMRTVTNYFLLNLSIADLLMSSLNCVFNFIF 143
            || :..:|::.:..::.:|:.||.||:||:..|:.||||||||||||:.:|..|::.|.:.||::
Zfish    22 PW-RVALWSVAYSSILAIAVFGNLIVMWIILAHKRMRTVTNYFLLNLAFSDASMAAFNTLINFVY 85

  Fly   144 MLNSDWPFGSIYCTINNFVANVTVSTSVFTLVAISFDRYIAIVHPLKRRTSRRKVRIILVLIWAL 208
            ..:.||.||..||..:||....:|..|::::.||:.|||:||:||||.|.|....::|:|.||.|
Zfish    86 ATHGDWYFGEAYCKFHNFFPVTSVFASIYSMSAIAVDRYMAIIHPLKPRLSATATKVIIVCIWVL 150

  Fly   209 SCVLSAPCLLYSSIMTKHYYNGKSRTVCFMMWPDGRYPTSMADYAYNLIILVLTYGIPMIVMLIC 273
            :.||:.|...:|:|...     ..||:|::.||    ..|...:.|::|:.:|.|.:|::||.|.
Zfish   151 AVVLAFPLCFFSTIKKL-----PKRTLCYVAWP----RPSEDPFMYHIIVAMLVYVLPLVVMGIN 206

  Fly   274 YSLMGRVLWGSRSIGENTDRQMESMKSKRKVVRMFIAIVSIFAICWLPYHLFFIYAYHNNQVAST 338
            |:::|..|||....|:::|.....:::|||||:|.|.:|..||.||||||::|:....|.|:|..
Zfish   207 YTIVGLTLWGGEIPGDSSDNYQGQLRAKRKVVKMMIIVVVTFAFCWLPYHVYFLVTGLNKQLARW 271

  Fly   339 KYVQHMYLGFYWLAMSNAMVNPLIYYWMNKRFRMYFQRIICCCCVGLTRHRFDSPKSRLTNKNSS 403
            |::|.:||...|||||:.|.||:||..:|.|||..|:|:...|           |..::::.:..
Zfish   272 KFIQQIYLSIMWLAMSSTMYNPIIYCCLNSRFRAGFKRVFRWC-----------PFVQVSDYDEL 325

  Fly   404 NRHTRGGYTVAHSLPNSSPPTTQTLLAVLAQTLTQP-KPQTQ----LLLSHHSPHPTQPSAAETK 463
            ...     .:.|.:...|...|.:.:.....|:..| :|.||    .||:||..|....:.|::|
Zfish   326 ELR-----AMRHKVARQSSMYTMSRMETTVVTVCDPSEPNTQPGRKSLLNHHHHHNGCSNPAKSK 385

  Fly   464  463
            Zfish   386  385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR86C	NP_001097741.1	7tmA_TACR	84..374	CDD:320512	118/289 (41%)
		TM helix 1	85..111	CDD:320512	8/25 (32%)
		TM helix 2	118..144	CDD:320512	13/25 (52%)
		TM helix 3	156..186	CDD:320512	11/29 (38%)
		TM helix 4	197..218	CDD:320512	8/20 (40%)
		TM helix 5	251..280	CDD:320512	10/28 (36%)
		TM helix 6	299..329	CDD:320512	17/29 (59%)
		TM helix 7	342..367	CDD:320512	13/24 (54%)
tacr3a	NP_001243567.1	7tm_GPCRs	26..307	CDD:475119	118/289 (41%)
		TM helix 1	28..52	CDD:320669	8/23 (35%)
		TM helix 2	61..83	CDD:320669	10/21 (48%)
		TM helix 3	99..121	CDD:320669	6/21 (29%)
		TM helix 4	142..158	CDD:320669	7/15 (47%)
		TM helix 5	185..208	CDD:320669	8/22 (36%)
		TM helix 6	238..260	CDD:320669	12/21 (57%)
		TM helix 7	275..300	CDD:320669	13/24 (54%)