DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment TkR86C and P2RY1

DIOPT Version :9

Sequence 1:NP_001097741.1 Gene:TkR86C / 41286 FlyBaseID:FBgn0004841 Length:555 Species:Drosophila melanogaster
Sequence 2:NP_002554.1 Gene:P2RY1 / 5028 HGNCID:8539 Length:373 Species:Homo sapiens


Alignment Length:323 Identity:77/323 - (23%)
Similarity:145/323 - (44%) Gaps:59/323 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly    76 YELPWEQKTIWAIIFGLMMFVAIAGNGIVLWIVTGHRSMRTVTNYFLLNLSIADLLMSSLNCVFN 140
            |.||        .::.|:..:...||.:.:|:...|....:..:.::.||::||.|.........
Human    52 YYLP--------AVYILVFIIGFLGNSVAIWMFVFHMKPWSGISVYMFNLALADFLYVLTLPALI 108

  Fly   141 FIFMLNSDWPFGSIYCTINNFVANVTVSTSVFTLVAISFDRYIAIVHPLKR--RTSRRKVRIILV 203
            |.:...:||.||...|.:..|:.:|.:..|:..|..||..||..:|:|||.  |..::....|.|
Human   109 FYYFNKTDWIFGDAMCKLQRFIFHVNLYGSILFLTCISAHRYSGVVYPLKSLGRLKKKNAICISV 173

  Fly   204 LIWALSCVLSAPCLLYSSIMTKHYYNGKSRTV-CFMMWPDGRYPTSMADY-----AYNLIILVLT 262
            |:|.:..|..:|.|.||....:     |::|: |        |.|:..:|     .|::...|..
Human   174 LVWLIVVVAISPILFYSGTGVR-----KNKTITC--------YDTTSDEYLRSYFIYSMCTTVAM 225

  Fly   263 YGIPMIVMLICYSLMGRVLWGSRSIGENTDRQMESMKSKRKVVRMFIAIVSIFAICWLPYHLF-- 325
            :.:|::::|.||.|:.|.|         ..:.:::...:||.:.:.|.::::||:.::|:|:.  
Human   226 FCVPLVLILGCYGLIVRAL---------IYKDLDNSPLRRKSIYLVIIVLTVFAVSYIPFHVMKT 281

  Fly   326 ------------FIYAYHNNQVASTKYVQHMYLGFYWLAMSNAMVNPLIYYWMNKRFRMYFQR 376
                        .:.|: |::|.:|..|..      .||..|:.|:|::|:.....||....|
Human   282 MNLRARLDFQTPAMCAF-NDRVYATYQVTR------GLASLNSCVDPILYFLAGDTFRRRLSR 337

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
TkR86CNP_001097741.1 7tm_4 92..376 CDD:304433 73/305 (24%)
7tm_1 100..363 CDD:278431 69/284 (24%)
P2RY1NP_002554.1 7tmA_P2Y1 52..335 CDD:320499 76/319 (24%)
TM helix 1 52..79 CDD:320499 7/34 (21%)
TM helix 2 86..111 CDD:320499 6/24 (25%)
TM helix 3 124..154 CDD:320499 9/29 (31%)
TM helix 4 166..188 CDD:320499 6/21 (29%)
TM helix 5 214..243 CDD:320499 7/28 (25%)
TM helix 6 253..283 CDD:320499 7/29 (24%)
TM helix 7 303..328 CDD:320499 8/30 (27%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.