Protein Alignment TkR86C and AstA-R1

DIOPT Version :10

• Sequence 1: NP_001097741.1
• Gene: TkR86C / 41286
• FlyBaseID: FBgn0004841
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_524700.1
• Gene: AstA-R1 / 44126
• FlyBaseID: FBgn0266429
• Length: 394
• Species: Drosophila melanogaster
• Alignment Length: 345
• Identity: 97/345 - (28%)
• Similarity: 168/345 - (48%)
• Gaps: 47/345 - (13%)

  Fly    84 TIWAIIFGLMMFVAIAGNGIVLWIVTGHRSMRTVTNYFLLNLSIADLLMSSLNCVFNFIFMLNSD 148
            ||..:.||::.|..:.|||:|:.:|..::.||:.||..::||:::|:|.......|.....:..:
  Fly    75 TIVPVFFGIIGFAGLLGNGLVILVVVANQQMRSTTNLLIINLAVSDILFVIFCVPFTATDYVLPE 139

  Fly   149 WPFGSIYCTINNFVANVTVSTSVFTLVAISFDRYIAIVHPLKRRTSR--RKVRIILVLIWALSCV 211
            ||||:::|....::..||...||:|||.:||||::|:|||:...:.|  |...:.::..|.....
  Fly   140 WPFGNVWCKFVQYMIVVTCHCSVYTLVLMSFDRFLAVVHPVTSMSLRTERNATLAIMCAWITIVT 204

  Fly   212 LSAPCLLYSSIMTKHYYNGKSRTVCFMMWPDGRYPTSMADYAYNLI-----ILVLTYGIPMIVML 271
            .:.|..|..|:.. :.|:|.:.|.|..         |..:..::|:     ..:.:|..|:  .|
  Fly   205 TAIPVALSHSVRI-YQYHGNAGTACVF---------STEEEIWSLVGFQVSFFLSSYVAPL--TL 257

  Fly   272 ICYSLMGRV--LWGSRSIGENTDRQMESMKSKRKVVRMFIAIVSIFAICWLPYHLFFIYAYHNNQ 334
            ||:..||.:  ||.|   ........||.|.||:|.||.:.:|..|||||||.|:..:....|..
  Fly   258 ICFLYMGMLARLWKS---APGCKPSAESRKGKRRVTRMVVVVVLAFAICWLPIHVILVLKALNLY 319

  Fly   335 VAS-----TKYVQHMYLGFYWLAMSNAMVNPLIYYWMNKRFRMYFQRIICCCCVGLTRHRFDSPK 394
            ..|     .:.:.|:      :|.:|:.:||::|.:::..||..|::::.|          .||.
  Fly   320 GGSHLSVIIQIISHV------VAYTNSCINPILYAFLSDNFRKAFRKVVWC----------GSPP 368

  Fly   395 SRLTNK--NSSNRHTRGGYT 412
            ..:||:  ..:.|...|..|
  Fly   369 PLMTNQQVTKTTRTATGNGT 388

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR86C	NP_001097741.1	7tmA_TACR	84..374	CDD:320512	88/303 (29%)
		TM helix 1	85..111	CDD:320512	9/25 (36%)
		TM helix 2	118..144	CDD:320512	7/25 (28%)
		TM helix 3	156..186	CDD:320512	13/29 (45%)
		TM helix 4	197..218	CDD:320512	2/20 (10%)
		TM helix 5	251..280	CDD:320512	8/33 (24%)
		TM helix 6	299..329	CDD:320512	15/29 (52%)
		TM helix 7	342..367	CDD:320512	6/24 (25%)
AstA-R1	NP_524700.1	7tmA_AstA_R_insect	75..358	CDD:320224	88/303 (29%)
		TM helix 1	76..102	CDD:320224	9/25 (36%)
		TM helix 2	109..135	CDD:320224	7/25 (28%)
		TM helix 3	147..177	CDD:320224	13/29 (45%)
		TM helix 4	189..209	CDD:320224	2/19 (11%)
		TM helix 5	239..268	CDD:320224	8/30 (27%)
		TM helix 6	284..314	CDD:320224	15/29 (52%)
		TM helix 7	326..351	CDD:320224	6/30 (20%)